HOW TO SELECT AN APPROPRIATE PRODUCT

For successful outcomes, choice of CTPs for each case may be guided by criteria outlined in Algorithm 1 below.

Criteria relevant for decision making is also itemized below: 

• Evidence, as defined by availability of RCTs
• Careful weighing of benefits and harms, appropriate product selection for the wound condition
• • CTP indications, contraindications and features 
  • Shelf-life: length until expiration date, storage requirements (room temperature, freezer, refrigerator), need for special equipment for application
• Patient’s and clinician’s preference and familiarity with the product
• • Dietary beliefs, religious beliefs, moral beliefs
  • Compliance with post-application care
• Availability of resources and cost-effectiveness
• • Reimbursement
  • • See section ‘Coding, Coverage and Reimbursement’ in topic "Cellular and/or Tissue Products" 
    • Care setting
    • Pre-authorization requirements
    • Patient co-pay
• Adherence to standard of care [1] :
• • Meticulous wound bed preparation, including removal of exudate and necrotic tissue, infection control, nutritional support, pressure avoidance (e.g., offloading for diabetic foot ulcers and pressure ulcers) and edema control (e.g., compression for venous leg ulcers).
  • Diligent patient preparation and correction of systemic cofactors that impair healing;
  • Aggressive correction of the underlying wound etiology;
  • Proper CTP application; appropriate cover dressings;
  • Consistent, regular monitoring of both the cover dressings and the wound bed