Gibbons GW
Advances in wound care. Date of publication 2015 Sep 1;volume 4(9):534-544.
1. Adv Wound Care (New Rochelle). 2015 Sep 1;4(9):534-544. doi:
10.1089/wound.2015.0647.
Grafix(®), a Cryopreserved Placental Membrane, for the Treatment of
Chronic/Stalled Wounds.
Gibbons GW(1).
Author information:
(1)South Shore Hospital Center for Wound Healing , Weymouth, Massachusetts.
Objective: To discuss the use of Grafix®, a commercially available,
cryopreserved placental membrane, for the treatment of chronic/stalled wounds of
different etiologies. Approach: To describe the unique composition of Grafix, to
provide an overview of the existing clinical evidence supporting the benefits of
Grafix for wound treatment, and to share the experience of the South Shore
Hospital Center for Wound Healing (Weymouth, MA) with Grafix for the treatment
of nonhealing wounds. Results: Clinical evidence supports the safety and
efficacy of Grafix for the treatment of chronic/stalled wounds, including those
that have failed other advanced treatment modalities. Innovation: Grafix is a
cryopreserved placental membrane manufactured utilizing a novel technology that
enables the preservation of all placental membrane components in their native
state. Placental membranes have a unique composition of extracellular matrix,
growth factors, and cells (including mesenchymal stem cells), which makes this
tissue unique among other advanced biological wound treatment modalities.
Conclusion: Clinical evidences support the benefits of Grafix for head-to-toe
wound treatment.
DOI: 10.1089/wound.2015.0647
PMCID: PMC4529022
PMID: 26339532
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