Octarica SG, Ellistasari EY, Dewi AK, Sambodo SL, Utama RFD, Adjie SP, et al.
Acta dermatovenerologica Alpina, Pannonica, et Adriatica. Date of publication 2025 Sep 1;volume 34(3):101-107.
1. Acta Dermatovenerol Alp Pannonica Adriat. 2025 Sep;34(3):101-107.
Preventive and curative approaches to diaper dermatitis in children: a
systematic review.
Octarica SG(1)(2), Ellistasari EY(1)(2), Dewi AK(1)(2), Sambodo SL(1)(2), Utama
RFD(1)(2), Adjie SP(1)(2).
Author information:
(1)Dermatology Department, Faculty of Medicine, Sebelas Maret University,
Surakarta, Indonesia.
(2)Dr. Moewardi General Hospital, Surakarta, Indonesia.
Diaper dermatitis (DD) is a common inflammatory skin condition in the diaper
area of infants, caused by a combination of host and environmental factors, such
as moisture, friction, elevated skin pH, and prolonged exposure to urine and
feces. This systematic review analyzed 13 studies involving 2,935 children to
evaluate effective treatment and prevention strategies for DD. Key interventions
identified include the use of disposable and emollient-containing diapers,
gentle skincare practices (such as bathing every 1 to 2 days with mild cleansers
and emollients), and pH-balanced wet wipes. Frequent diaper changes and allowing
diaper-free time also help reduce skin irritation. Topical treatments,
particularly emollients with zinc oxide or dexpanthenol, were found to be highly
effective with minimal side effects. Preventive measures, such as using
superabsorbent disposable diapers, regular application of barrier creams, and
maintaining good hygiene, are crucial in reducing the incidence and severity of
DD. In conclusion, a combined approach of proper diaper selection, gentle
skincare, and judicious use of topical emollients is recommended for both
treatment and prevention of DD in children.
PMID: 41014074 [Indexed for MEDLINE]
