Celebi ARC
Clinical ophthalmology (Auckland, N.Z.). Date of publication 2021 Aug 13;volume 15():3443-3457.
1. Clin Ophthalmol. 2021 Aug 13;15:3443-3457. doi: 10.2147/OPTH.S224192.
eCollection 2021.
Hyperbaric Oxygen Therapy for Central Retinal Artery Occlusion: Patient
Selection and Perspectives.
Celebi ARC(1).
Author information:
(1)Atakent Education and Research Hospital, Department of Ophthalmology,
Acibadem University School of Medicine, Istanbul, Turkey.
The central retinal artery occlusion (CRAO) is a rare ophthalmological emergency
that can occur in the eye. CRAO can affect persons of any age, however it is
most common in people over the age of 60. CRAO is associated with a number of
risk factors, including giant cell arteritis, carotid artery atherosclerosis,
cardiogenic emboli, hypertension, smoking, diabetes, and thromboembolic disease.
The chance of each of these etiologies being present is assessed during the
course of the investigation. Hyperbaric oxygen treatment (HBOT) is classified by
the American Heart Association for CRAO at level IIb. In accordance with that,
HBOT might be considered for the treatment of such a severe condition. HBOT can
maintain retinal oxygenation during ischemic events by allowing oxygen to
diffuse through choroidal capillaries that have been exposed to elevated partial
pressures of oxygen. As a result, ischemia-related damage is reversed if applied
within proper time frame. The amount of time that has passed prior to initiation
of HBOT is considered to be the most critical factor in determining the best
visual prognosis. According to the Undersea and Hyperbaric Medical Society,
patients who are identified with CRAO after the onset of symptoms should be
evaluated for HBOT within 24 hours. HBOT has the advantage of having a low risk
profile, and it can be utilized to improve visual outcomes in proper patients.
© 2021 Celebi.
DOI: 10.2147/OPTH.S224192
PMCID: PMC8370578
PMID: 34413628
Conflict of interest statement: The author reports no conflicts of interest in
this work.
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