Savvidou OD, Kaspiris A, Bolia IK, Chloros GD, Goumenos SD, Papagelopoulos PJ, Tsiodras S, et al.
Orthopedics. Date of publication 2018 Jul 1;volume 41(4):193-199.
1. Orthopedics. 2018 Jul 1;41(4):193-199. doi: 10.3928/01477447-20180628-02.
Effectiveness of Hyperbaric Oxygen Therapy for the Management of Chronic
Osteomyelitis: A Systematic Review of the Literature.
Savvidou OD, Kaspiris A, Bolia IK, Chloros GD, Goumenos SD, Papagelopoulos PJ,
Tsiodras S.
Hyperbaric oxygen has been used as an adjunctive measure in the treatment of
chronic osteomyelitis. The aim of this systematic literature review was to
analyze the outcome and the complications of hyperbaric oxygen for chronic
osteomyelitis. Forty-five of 96 studies reporting the use of hyper-baric oxygen
for 460 patients with chronic osteomyelitis met the inclusion criteria and were
analyzed qualitatively. All patients previously received antibiotics and surgical
debridement. Mixed bacterial flora was detected in most of the studies.
Staphylococcus aureus was the isolated pathogen in 12 (60%) of the 20 cohort and
in 4 (20%) of the 20 case studies. Adjuvant hyperbaric oxygen was effective in 16
(80%) of the 20 cohort and 19 (95%) of the 20 case studies. Overall, 308 (73.5%)
of 419 patients with complete data had a successful outcome and no reported
relapse. Available evidence supports a potentially beneficial role of adjunctive
hyperbaric oxygen, especially in refractory cases of chronic osteomyelitis.
[Orthopedics. 2018; 41(4):193-199.].
Copyright 2018, SLACK Incorporated.
DOI: 10.3928/01477447-20180628-02
PMID: 30035798 [Indexed for MEDLINE]
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