Demidova-Rice TN, Hamblin MR, Herman IM, et al.
Advances in skin & wound care. Date of publication 2012 Jul 1;volume 25(7):304-14.
1. Adv Skin Wound Care. 2012 Jul;25(7):304-14. doi:
10.1097/01.ASW.0000416006.55218.d0.
Acute and impaired wound healing: pathophysiology and current methods for drug
delivery, part 1: normal and chronic wounds: biology, causes, and approaches to
care.
Demidova-Rice TN(1), Hamblin MR, Herman IM.
Author information:
(1)E.L. Steele Laboratory of Tumor Biology, Massachusetts General Hospital,
Boston, USA.
This is the first installment of 2 articles that discuss the biology and
pathophysiology of wound healing, review the role that growth factors play in
this process, and describe current ways of growth factor delivery into the wound
bed. Part 1 discusses the latest advances in clinicians' understanding of the
control points that regulate wound healing. Importantly, biological similarities
and differences between acute and chronic wounds are considered, including the
signaling pathways that initiate cellular and tissue responses after injury,
which may be impeded during chronic wound healing.
DOI: 10.1097/01.ASW.0000416006.55218.d0
PMCID: PMC3428147
PMID: 22713781 [Indexed for MEDLINE]
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