Goldenberg G, Jorizzo JL, et al.
The Journal of dermatological treatment. Date of publication 2005 Jan 1;volume 16(5-6):347-9.
1. J Dermatolog Treat. 2005;16(5-6):347-9.
Use of etanercept in treatment of pyoderma gangrenosum in a patient with
autoimmune hepatitis.
Goldenberg G(1), Jorizzo JL.
Author information:
(1)Department of Dermatology, Wake Forest University School of Medicine, Winston-
Salem, NC 27157, USA.
A 30-year-old female with past medical history of autoimmune hepatitis was sent
to our clinic for consultation and treatment of refractory pyoderma gangrenosum
(PG) of bilateral lower extremities. At the time of presentation, she had failed
treatment with prednisone, azathioprine and local wound care. Treatment options
were limited by the patient's autoimmune hepatitis. This patient was treated with
etanercept and a taper of oral prednisone, which resulted in a complete clinical
cure of her PG. More studies are needed to evaluate the safety and efficacy of
etanercept for PG in patients with liver disease.
DOI: 10.1080/09546630500424722
PMID: 16428159 [Indexed for MEDLINE]
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