Michaëlsson G, Molin L, Ohmann S, Gip L, Lindström B, Skogh M, Trolin I, et al.
Archives of dermatology. Date of publication 1976 Mar 1;volume 112(3):344-9.
1. Arch Dermatol. 1976 Mar;112(3):344-9.
Clofazimine. A new agent for the treatment of pyoderma gangrenosum.
Michaëlsson G, Molin L, Ohmann S, Gip L, Lindström B, Skogh M, Trolin I.
Eight patients had pyoderma gangrenosum. They were given a phendimetrazine
tartrate derivative, clofazimine (Lamprene [Britain]), which is a
chemotherapeutic agent used mainly in certain mycobacterial infections and which
also has phagocytosis-enhancing properties. The effect of this drug was
remarkably good, with rapid healing of the lesions commencing 3 to 14 days after
treatment was started. The mechanism for the effect of clofazimine in pyoderma
gangrenosum is not known.
PMID: 1259447 [Indexed for MEDLINE]
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