Lobo Gajiwala A, Sharma V, et al.
Cell and tissue banking. Date of publication 2003 Jan 1;volume 4(2-4):147-50.
1. Cell Tissue Bank. 2003;4(2-4):147-50.
Use of irradiated amnion as a biological dressing in the treatment of radiation
induced ulcers.
Lobo Gajiwala A(1), Sharma V.
Author information:
(1)Tissue Bank, Tata Memorial Hospital, Parel, Mumbai 400 012, India; Author for
correspondence (Tel.: 91-022-24177112; Fax: 91-022-4146937; e-mail:
lobogajiwalaa@tmcmail.org, asklobog@vsnl.com)
The management of moist skin desquamation (ulceration) following radiation
therapy has been a concern since the inception of this therapy. The treatment of
skin reactions focuses on promoting healing, improving patient comfort preventing
infection and decreasing trauma to the area. Various dressings like topical
preparations, hydrocolloid and gentian violet 1 % dressing have been used for its
treatment. We present our experience with the use of amnion as a biological
dressing in patients with radiation induced ulceration following pelvic radiation
using megavoltage beam. The preliminary experience with treatment in 14 patients
proved to be cost effective due to a shorter duration of ulcer healing (median of
7 days), fewer dressing changes (median of 4 dressings) and diminished use of
analgesics.
DOI: 10.1023/B:CATB.0000007024.81019.03
PMID: 15256852
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