Iyer S, Balasubramanian D, et al.
Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons.... Date of publication 2012 May 1;volume 45(2):325-31.
1. Indian J Plast Surg. 2012 May;45(2):325-31. doi: 10.4103/0970-0358.101311.
Management of radiation wounds.
Iyer S(1), Balasubramanian D.
Author information:
(1)Department of Plastic and Reconstructive Surgery, Amrita Institute of Medical
Sciences, Kochi, Kerala, India ; Department of Head and Neck Surgery, Amrita
Institute of Medical Sciences, Kochi, Kerala, India.
Radiotherapy forms an integral part in cancer treatment today. It is used alone
or in combination with surgery and chemotherapy. Although radiotherapy is useful
to effect tumour death, it also exerts a deleterious effect on surrounding normal
tissues. These effects are either acute or can manifest months or years after the
treatment. The chronic wounds are a result of impaired wound healing. This
impairment results in fibrosis, nonhealing ulcers, lymphoedema and radionecrosis
amongst others. This article will discuss the pathophysiology in brief, along
with the manifestations of radiation-induced injury and the treatment available
currently.
DOI: 10.4103/0970-0358.101311
PMCID: PMC3495383
PMID: 23162232
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