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Unbiased information for educational purposes only. WoundReference does not produce, market, advertise, re-sell or distribute healthcare goods or services consumed by, or used on patients. For information about specific products, please contact the manufacturer directly.

Technology and Product Assessment:

Advograft Dual, per square centimeter

Product Type: Human Skin Allografts

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RMBB Health | |

HCPCS : Q4382 (Medicare DME co-payment per billable unit min / max: $0.00 / $0.00)

AdvoGraft Dual is a dehydrated, dual-layer placental allograft and biological covering.

INTENDED USES: AdvoGraft Dual can be used to provide structural integrity for deep or complex wounds. Advograft Dual supports wound closure of chronic diabetic foot ulcers, venous leg ulcers and pressure wounds. AdvoGraft Dual serves as a barrier to create an environment for remodeling of surgical and reconstructive wounds.

CLAIMED BENEFITS: AdvoGraft Membrane Dual combines amniotic and chorionic membranes to enhance coverage. Packaged sterile and ambient stable, it offers clinical convenience across care settings. Sterile, shelf-stable (15–30°C); no refrigeration or rehydration required. Designed for easy manipulation and anatomical contouring without tearing or curling.

Available Sizes:

2 x 2 cm

2 x 3 cm

2 x 4 cm

4 x 4 cm

4 x 6 cm

4 x 8 cm

10 x 15 cm

Wound Reference does not produce, market, re-sell or distribute health care goods or services consumed by, or used on, patients.

	Composition: Animal-derived
	Composition: Human dermis with/without epidermis
	Composition: Human placenta or umbilical cord
	Composition: Viable (living) cells
	Configuration: Fenestrated/ meshed
	Configuration: Flowable
	Configuration: Sheet
	May apply on full-thickness wounds
	May apply over exposed tendon/ bone/ muscle
	May apply over infected tissue
	Processing: Cryopreserved
	Processing: Decellularized or irradiated
	Processing: Dehydrated
	Processing: Fresh (limited shelf life)
	Processing: Hydrated
	Processing: Minimally manipulated
	Shelf life: Greater than 2 years
	Storage: refrigeration needed
	Storage: room temp

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Application of Skin Substitutes (also known as Cellular and/or Tissue Based Products) to certain wounds may help these wounds heal faster than conventional dressings and conservative treatments. Usually skin substitutes are used if conventional treatment has been tried for at least 30 days and the wound has not healed as quickly as expected. Human skin allografts are a type of skin substitute. They are made of skin donated by human donors that have had intact cells removed or treated to avoid immunologic rejection (a process in which the body of the person receiving the skin substitute kills the cells of the skin substitute).

For Medicare to cover this product, it needs to be ordered and applied by your clinician. A patient cannot purchase it directly from a Durable Medical Equipment (DME) store and receive reimbursement for it.

Go to Advograft Dual

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* Wound Reference does not produce, market, re-sell or distribute health care goods or services consumed by, or used on, patients.
** We do not accept paid advertising to guarantee unbiased product information

Important Notice: The product information contained on this page, including the product images and additional product materials, was collected from various supplier sources. All product claims and specifications are those of the product suppliers. Every effort has been made to ensure the accuracy of the product information, however on occasion manufacturers may alter their products or packaging without notice. Wound Reference assumes no liability for inaccuracies or misstatements about products. The properties of a product may change or be inaccurate following the posting or printing of the product information in the document, either in the print or online version. Due to product changes, information listed in this document is subject to change without notice. We recommend that you always read labels, warnings and instructions for use before using a product. Content on this site is for reference purposes and is not intended to be a substitute for professional advice given by a physician or other licensed healthcare professional.

Advograft Dual, per square centimeter

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