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Composite matrix

Composite matrix

Composite matrix


Composite Matrices are derived from human keratinocytes and fibroblasts supported by a scaffold of synthetic mesh or xenogeneic collagen. These are also referred to as human skin equivalent but are unable to be used as autografts due to immunologic rejection or degradation of the living components by the host. Active cellular components continue to generate bioactive compounds and protein that may accelerate wound healing and epithelial regrowth. [1]

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  1. CGS Administrators, LLC et al. LCD: Wound Application of Cellular and/or Tissue Based Products (CTPs), Lower Extremities (L36690) . 2022;.
Topic 19 Version 1.0



Human Skin Allografts are bioengineered from human skin components and human tissue which have had intact cells removed or treated to avoid immunologic rejection.

Allogeneic Matrices are cellular and/or tissue products usually derived from human neonatal fibroblasts of the foreskin, and may contain metabolically active or regenerative components

Skin Substitute:Duration of ulcer - approximately 89 weeksWound free of infection, osteomyelitis, surrounding cellulitis, tunnels/tracts, necrotic tissue - yesInitial Application/Reapplication - 3rd applicationSkin substitute used - Grafix PrimeMethod of fixation - Mepitel, steristripsLot # - A160300Unit # - 16003Part # - PS60013Expiration date - 6/14/18