BIOSTEP Collagen Matrix

Last updated on 12/25/25 | First published on 12/25/25 | Literature review current through Dec. 2025 [cite]

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Technology and Product Assessment

Product Type: Collagen

Unbiased information for educational purposes only. WoundReference does not produce, market, advertise, re-sell or distribute healthcare goods or services consumed by, or used on patients. For information about specific products, please contact the manufacturer directly.

Description: Biostep Collagen Dressing is a collagen matrix dressing with both type I collagen and denatured collage.

INTENDED USES: Management of full-thickness and partial-thickness acute and chronic wounds including: Pressure ulcers, Diabetic ulcers, Ulcers caused by mixed vascular etiologies, Venous ulcers, First and second degree burns, Donor/graft sites, Abrasions, Dehisced surgical wounds, Traumatic wounds healing by secondary intention

CLAIMED BENEFITS: The carboxymethylcellulose (CMC) and alginate components of BIOSTEP and BIOSTEP AG help absorb moisture. The CMC within dressing gels on contact with moisture providing improved patient comfort by creating a soothing, cooling effect upon application, CMC within dressing adds structure for easy application when moist. Highly conformable to ensure close contact with wound bed. The gelatin component of BIOSTEP and BIOSTEP Ag provides enhanced signaling to the cells responsible for creating granulation tissue.

OPTION: [2" x 2", 10 eaches] REPLACE info for each SKU

Manufacturer: Smith & Nephew, Inc.

Information retrieved from manufacturer and/or FDA-approved labels

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ESSENTIALS

Product

Estimated
Out-of-pocket
Cost

HCPCS Class

HCPCS

BIOSTEP Collagen Dressing, 2" x 2", 10 eaches

Collagen dressing, sterile, size 16 sq. in. or less, each

A6021

BIOSTEP Collagen Dressing, 4" x 4", 10 eaches

Collagen dressing, sterile, size 16 sq. in. or less, each

A6021

* Hover on the information button next to each header for detailed explanation on the type of information provided by the table

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DME coverage and co-payment

Product

Estimated
Out-of-pocket
Cost

Patient DME Co-Payment per Billable Unit

DME Reimbursement to Suppliers

Frequency Replacement if Requirements Met

Office and/or Facility - Product reimbursement

Smith & Nephew, Inc.
BIOSTEP Collagen Dressing, 2" x 2", 10 eaches

$5.99
each

$29.97

1 changes/week

Smith & Nephew, Inc.
BIOSTEP Collagen Dressing, 4" x 4", 10 eaches

$5.99
each

$29.97

1 changes/week

* Every effort has been made to ensure the accuracy of the product information, however you should visit the manufacturer's website for the latest information.

* Hover on the information button next to each header for detailed explanation on the type of information provided by the table

Product

Estimated
Out-of-pocket
Cost

Recom / Evidence

FDA Safety

Quality Measures

Cost Effectiveness

BIOSTEP Collagen Dressing, 2" x 2", 10 eaches

Coming soon

BIOSTEP Collagen Dressing, 4" x 4", 10 eaches

Coming soon

Product

Estimated
Out-of-pocket
Cost

Features

BIOSTEP Collagen Dressing, 2" x 2", 10 eaches

Application: Can be used as primary dressing Depth: Full thickness (deep) Depth: Partial thickness (shallow) Exudate: Dry Exudate: Low Exudate: Moderate Exudate: High Indications: May be applied over infected tissue Indications: May be used to pack deep wounds Indications: May be used under compression Medicare freq of replacement: 1/day Wear time: Up to 3 days

BIOSTEP Collagen Dressing, 4" x 4", 10 eaches

No CPT codes to display.

Hover on the information button next to each header for detailed explanation on the type of information provided by the table
The information provided on this website is informational only. This is not a guarantee of Reimbursement Rates, nor is it intended to make recommendations regarding clinical practices. Information on this website is subject to change with out notice due to changes in reimbursement laws, regulations, rules and policies. The ultimate responsibility for correct coding lies with the provider of services. Please contact the appropriate payer for their interpretation of the appropriate code to use for the procedure.
CPT® is a registered trademark of the American Medical Association. All CPT codes and descriptions are copyrighted 2018, American Medical Association. All rights reserved. CPT codes and CPT descriptions are from the current manuals and those included herein are not intended to be all-inclusive and are included for informational purposes only. Codes referenced on Wound Reference are for informational purposes only. Inclusion or exclusion of any codes does not guarantee coverage. Providers should reference the American Medical Association prior to the submission of claims for reimbursement of covered services.

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Other related brands: Endoform Dermal Template Dressing, 5 cm x 5 cm, 10/box, Puracol Plus Collagen Wound Dressing, 2" x 2.25", box o..., FIBRACOL™ Plus Collagen Wound Dressing With Alginate, 2..., Cutimed Epiona, 2" x 2" (5.1cm x 5.1cm),10/Pack, DermaCol 100 Type 1 Bovine Collagen Powder Wound Filler..., Medifill™ II Particles, 1.0 gm, Stimulen Collagen Wound Dressing, Powder Sachet, 1 gram..., Endoform Dermal Template Dressing, 5 cm x 5 cm fenestra..., FIBRACOL™ Plus Collagen Wound Dressing With Alginate, 4..., FIBRACOL™ Plus Collagen Wound Dressing With Alginate, 4..., FIBRACOL™ Plus Collagen Wound Dressing With Alginate, 3..., DermaCol Collagen Matrix Dressing, 2 X 2 Inch, Square, ..., Cutimed Epiona, 8" x 8" (20cm x 20cm),10/Pack, SilvaKollagen Gel Silver Collagen Wound Gel, 1.5 oz Tub..., Simpurity Collagen Particles, 1 Gram Vial, Endoform Dermal Template Dressing, 10 cm x 12.7 cm fene..., Suprasorb C Collagen Dressing, 6 x 8 x 0.8cm, case of 5, Cutimed Epiona, 4" x 4" (10cm x 10cm), 10/Pack, HYCOL® HYDROLYZED COLLAGEN, 1 g, box of 10, Endoform Dermal Template Dressing, 10 cm x 12.7 cm, 10/..., CellerateRX® Surgical Powder. 5 g, each, Suprasorb C Collagen Dressing, 4 x 6 x 0.8cm, case of 5, HYCOL® HYDROLYZED COLLAGEN, 10 g, box of 10, Suprasorb C Collagen Dressing, 8 x 12 x 0.8cm, case of ..., CellerateRX® Surgical Powder. 1 g, each,

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NOTE: This is a controlled document. This document is not a substitute for proper training, experience, and exercising of professional judgment. While every effort has been made to ensure the accuracy of the contents, neither the authors nor the Wound Reference, Inc. give any guarantee as to the accuracy of the information contained in them nor accept any liability, with respect to loss, damage, injury or expense arising from any such errors or omissions in the contents of the work.

Topic 1699 Version 1.0

BIOSTEP Collagen Matrix

BIOSTEP Collagen Matrix

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