O'Quinn R, Aldridge C, Sax DS, et al.
Wounds : a compendium of clinical research and practice. Date of publication 2025 Mar 1;volume 37(3):102-106.
1. Wounds. 2025 Mar;37(3):102-106. doi: 10.25270/wnds/24117.
Post-Mohs surgical wounds treated with intact fish skin graft: a multicenter
analysis.
O'Quinn R(1), Aldridge C(1), Sax DS(2).
Author information:
(1)South Texas Skin Cancer Center, San Antonio, TX, USA.
(2)University Park Dermatology, Sarasota, FL, USA.
BACKGROUND: Intact fish skin graft (IFSG) has been reported to be an adjunct to
healing post-Mohs surgical wounds.
OBJECTIVE: To assess the data that could be found on the use of IFSG in
conjunction with Mohs surgery.
MATERIALS AND METHODS: A non-interventional observational registry collected
data on the use, indications, and outcomes of IFSG over 32 weeks. This registry
collected data on IFSG placed for a broad variety of indications. The primary
end point was to determine the percentage of wounds closed at 32 weeks, and the
secondary objective was to determine the median number of IFSG applications
during this period. The registry was queried for patients who had IFSG placed
for wounds created by Mohs surgery.
RESULTS: As of mid-April 2024, 41 participants enrolled in the registry had
undergone placement of IFSG post-Mohs surgery. The mean (standard deviation)
patient age was 77.6 (8.9) years, and 24% of participants were female (n = 10).
Forty of 41 wounds (97.6%) achieved complete wound closure in a median of 5
weeks, and the median number of visits was 5. For closed wounds, the median
number of applications was 2.
CONCLUSION: This registry demonstrates that in a real-world setting, IFSG
provides support to aid wound closure. In the post-Mohs setting, only 1 to 2
IFSG applications were required. This study demonstrates how IFSG can be a
viable option for Mohs surgeons to consider in the reconstruction paradigm for a
variety of wound sizes and anatomic locations.
DOI: 10.25270/wnds/24117
PMID: 40215359 [Indexed for MEDLINE]
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