Author(s) Ivana J, Sanjaya IGPH, et al.

Journal European burn journal. Date of publication 2025 Sep 8;volume 6(3):.

Abstract 1. Eur Burn J. 2025 Sep 8;6(3):50. doi: 10.3390/ebj6030050. Evaluation of the Efficacy of Fish Skin Grafts as Wound Dressings: A Systematic Review. Ivana J(1), Sanjaya IGPH(2). Author information: (1)Faculty of Medicine, Udayana University, Bali 80234, Indonesia. (2)Division of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Udayana University, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Bali 80113, Indonesia. The use of fish skin grafts as xenografts is a promising alternative for wound healing. Several studies have shown fish skin grafts to be a safer and more effective option compared to other alternatives, due to the large amount of fatty acids, including omega-3, which have been proven to promote wound healing. The purpose of this study was to evaluate the efficacy of fish skin grafts as wound dressing. A literature search up to March 2024 was conducted using the electronic databases of PubMed, Cochrane, and ScienceDirect. A total of 158 patients from six studies were included in this systematic review. All studies showed early wound healing using fish skin grafts; one study showed that wound healing was halved compared to paraffin gauze. Complete wound healing using fish skin grafts was noted as early as 30 days. Out of 114 patients treated with fish skin grafts, 1 patient showed signs of infection, and no patients showed allergic reactions. One study also found that fish skin grafts provide satisfactory wound scar quality. This study concludes that fish skin grafts are a great alternative and should be considered in wound treatment. The high omega-3 component that is preserved in fish skin grafts promotes faster wound healing and contains antibacterial agents that prevent infection. However, randomized control trials with a larger sample size are recommended to further assess the efficacy of fish skin grafts. DOI: 10.3390/ebj6030050 PMCID: PMC12452568 PMID: 40981098 Conflict of interest statement: The authors declare no conflicts of interest.

Source ID (e.g. PMID): 40981098