Sheikh ES, Sheikh ES, Fetterolf DE, et al.
International wound journal. Date of publication 2014 Dec 1;volume 11(6):711-7.
1. Int Wound J. 2014 Dec;11(6):711-7. doi: 10.1111/iwj.12035. Epub 2013 Feb 15.
Use of dehydrated human amniotic membrane allografts to promote healing in
patients with refractory non healing wounds.
Sheikh ES(1), Sheikh ES, Fetterolf DE.
Author information:
(1)Department of Clinical Medicine, Institute for Nerve, Hand & Reconstructive
Surgery, Rutherford, NJ, USA.
Non healing wounds present a significant social and economic burden. Chronic non
healing wounds are estimated to affect as many as 1-2% of individuals during
their lifetime, and account for billions of dollars of expense annually on both
a national and global basis. Our purpose is to describe the use of a novel
dehydrated amniotic membrane allograft (EpiFix(®) ; MiMedx Group, Inc.,
Kennesaw, GA) for the treatment of chronic non healing wounds. We describe the
results of EpiFix treatment in four patients who had not achieved wound closure
with both conservative and advanced measures, and had been referred for a
definitive plastic surgery procedure. Healing was observed in a variety of
wounds with one to three applications of the dehydrated amniotic membrane
material. The material was well tolerated by patients. Healed wounds did not
recur in long-term follow-up. Further investigation of the use of dehydrated
amniotic membrane in broader application to various types of dermal wounds
should be considered.
© 2013 The Authors. International Wound Journal © 2013 Medicalhelplines.com Inc
and John Wiley & Sons Ltd.
DOI: 10.1111/iwj.12035
PMCID: PMC7950830
PMID: 23409746 [Indexed for MEDLINE]
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