Hsia HC, Eriksson E, Gurtner GC, Veves A, Hamdy O, Margolis DJ, Armstrong DG, Lavery LA, Grice EA, Schultz G, Conte MS, Kirsner RS, Attinger CE, Steinberg JS, Evans KK, Weir D, Kim PJ, Orgill DP, Liechty KW, Rubin JP, et al.
Advances in wound care. Date of publication 2025 Aug 20;volume ():.
1. Adv Wound Care (New Rochelle). 2025 Aug 20. doi: 10.1177/21621918251366586.
Online ahead of print.
Management of Diabetic Wounds: Expert Panel Consensus Statement.
Hsia HC(1), Eriksson E(2), Gurtner GC(3), Veves A(4), Hamdy O(5), Margolis
DJ(6), Armstrong DG(7), Lavery LA(8), Grice EA(9), Schultz G(10), Conte MS(11),
Kirsner RS(12), Attinger CE(13), Steinberg JS(13), Evans KK(13), Weir D(14), Kim
PJ(8)(15), Orgill DP(16), Liechty KW(3), Rubin JP(17).
Author information:
(1)Departments of Surgery and Biomedical Engineering, Yale University, New
Haven, Connecticut, USA.
(2)Harvard Medical School, Boston, Massachusetts, USA.
(3)Department of Surgery, University of Arizona, Tucson, Arizona, USA.
(4)Joslin-Beth Israel Deaconess Foot Center and The Rongxiang Xu, MD, Center for
Regenerative Therapeutics, Beth Israel Deaconess Medical Center, Boston,
Massachusetts, USA.
(5)Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA.
(6)Department of Biostatistics, Epidemiology and Informatics, University of
Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
(7)From the Southwestern Academic Limb Salvage Alliance (SALSA), Department of
Surgery, Keck School of Medicine of USC, Los Angeles, California, USA.
(8)Department of Plastic Surgery, University of Texas Southwestern, Dallas,
Texas, USA.
(9)Department of Dermatology, Perelman School of Medicine, University of
Pennsylvania, Philadelphia, Pennsylvania, USA.
(10)University of Florida, Gainesville, Florida, USA.
(11)Division of Vascular and Endovascular Surgery, University of California San
Francisco, San Francisco, California, USA.
(12)University of Miami Hospital and Clinics Wound Center, University of Miami
Miller School of Medicine, Miami, Florida, USA.
(13)Department of Plastic and Reconstructive Surgery, MedStar Georgetown
University Hospital, Washington, District of Columbia, USA.
(14)Saratoga Hospital Center for Wound Healing and Hyperbaric Medicine,
Kissimmee, Florida, USA.
(15)Department of Orthopedic Surgery, University of Texas Southwestern, Dallas,
Texas, USA.
(16)Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical
School, Boston, Massachusetts, USA.
(17)Departments of Plastic Surgery and Bioengineering, and McGowan Institute of
Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Significance: The Wound Healing Foundation recognized the need for
consensus-based unbiased recommendations for the treatment of wounds. Consensus
statements on the treatment of chronic wounds and acute wounds have been
developed and published previously. The current publication on diabetic wounds
represents the next step in this process. Diabetic wounds constitute a major
problem. Population-based and meta-analytic studies indicate that the presence
of foot wounds in patients with diabetes increases their mortality risk by more
than twofold. The management of diabetic wounds requires consistent and
evidence-driven intervention to achieve optimal clinical outcomes. This
consensus statement provides the clinician with the necessary foundational
approaches to the causes, diagnosis, and therapeutic management of diabetic
wounds. Presented in a structured format, this is a useful guide for clinicians
and learners in all patient care settings. Recent Advances: Continuous glucose
monitoring and other new tools have facilitated better diabetes management and
the management of associated wounds. Diabetic limb salvage should focus on
achieving and optimizing function for the patient with diabetes rather than
preserving limb tissue at all costs. Critical Issues: Successful management of
diabetic wounds requires a multidisciplinary approach encompassing comprehensive
assessment, timely intervention, and collaborative care by the wound clinician
with providers who can address critical aspects to achieve healing, including
careful management of blood glucose levels, optimization of off-loading and
physical therapy, assessment and treatment of limb ischemia, control and
prevention of wound infection, and optimal pain management. Future Directions:
Emerging treatments offer hope and promise, but the heterogenicity of diabetic
wounds poses a challenge to performing good studies, which will be necessary to
advance new treatments for diabetic wounds.
DOI: 10.1177/21621918251366586
PMID: 40833358
