Shin JY, Roh SG, Lee NH, Yang KM, et al.
The international journal of lower extremity wounds. Date of publication 2017 Mar 1;volume 16(1):14-22.
1. Int J Low Extrem Wounds. 2017 Mar;16(1):14-22. doi: 10.1177/1534734617699318.
Influence of Epidemiologic and Patient Behavior-Related Predictors on Amputation
Rates in Diabetic Patients: Systematic Review and Meta-Analysis.
Shin JY(1)(2), Roh SG(1)(2), Lee NH(1)(2), Yang KM(1)(2).
Author information:
(1)1 Medical School of Chonbuk National University, Jeonju, Republic of Korea.
(2)2 Biomedical Research Institute of Chonbuk National University Hospital,
Jeonju, Republic of Korea.
Amputation of patients with diabetic foot is a major issue worldwide,
particularly from a medical and economic standpoint. This meta-analysis aimed to
identify significant risk factors of high amputation rate among epidemiologic and
patient behavior-related predictors in diabetic patients. A systematic literature
review and meta-analysis were performed using MEDLINE, EMBASE, and Cochrane
databases. Seven variables were extracted from the included studies and evaluated
based on amputation rate. The Newcastle-Ottawa scale was used to assess the
quality of the studies. The search strategy identified 101 publications. After
screening, 33 articles were selected for review. Male sex and smoking were
identified as significant risk factors of high amputation rate of diabetic foot.
Although further investigation of long-term and randomized controlled studies is
needed, we identified 2 variables as significant risk factors for high amputation
rate in diabetic patients in this meta-analysis.
DOI: 10.1177/1534734617699318
PMID: 28682679 [Indexed for MEDLINE]
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