Kajagar BM, Godhi AS, Pandit A, Khatri S, et al.
The Indian journal of surgery. Date of publication 2012 Oct 1;volume 74(5):359-63.
1. Indian J Surg. 2012 Oct;74(5):359-63. doi: 10.1007/s12262-011-0393-4. Epub 2012
Apr 11.
Efficacy of low level laser therapy on wound healing in patients with chronic
diabetic foot ulcers-a randomised control trial.
Kajagar BM(1), Godhi AS, Pandit A, Khatri S.
Author information:
(1)Department of Surgery, Jawaharlal Nehru Medical College, Nehru Nagar, Belgaum,
590 010 Karnataka India.
Foot ulcers are serious complications of Diabetes Mellitus (DM) and are known to
be resistant to conventional treatment. They may herald severe complications if
not treated wisely. Electromagnetic radiations in the form of photons are
delivered to the ulcers in laser form to stimulate healing. This study was
conducted to evaluate the efficacy of Low Level Laser Therapy (LLLT) in diabetic
ulcer healing dynamics. To determine mean percentage reduction of wound area in
study and control groups.SETTINGS: KLES Dr. Prabhakar Kore Hospital and Medical
Research Centre, Belgaum.
STUDY DESIGN: Randomized-Control Study.
METHODS: A total of 68 patients with Type 2 DM having Meggitt-Wagner Grade I foot
ulcers of atleast more than 4 weeks duration, less than 6 × 6 cm(2) with negative
culture were studied. Patients were randomized into two groups of 34 each.
Patients in study group received LLLT with conventional therapy and those in
control group were treated with conventional therapy alone. Healing or percentage
reduction in ulcer area over a period of 15 days after commencement of treatment
was recorded.
STATISTICAL ANALYSIS: Unpaired Student T Test and Mann Whitney U test. Mean age
of the patients was 50.94 years in control group and 54.35 years in study group
(p = 0.065). There was no significant difference between control and study group
with respect to mean FBS and HbA1c levels (p > 0.05), suggesting no biochemical
differences between two groups. Initial ulcer area was 2608.03 mm(2) in study
group and 2747.17 mm(2) in control group (p = 0.361). Final ulcer area was
1564.79 mm(2) in study group and 2424.75 mm(2) in control group (p = 0.361).
Percentage ulcer area reduction was 40.24 ± 6.30 mm(2) in study group and
11.87 ± 4.28 mm(2) in control group (p < 0.001, Z = 7.08). Low Level Laser
Therapy is beneficial as an adjunct to conventional therapy in the treatment of
diabetic foot ulcers (DFU).
DOI: 10.1007/s12262-011-0393-4
PMCID: PMC3477409
PMID: 24082586
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