Lavery LA, Boulton AJ, Niezgoda JA, Sheehan P, et al.
International wound journal. Date of publication 2007 Jun 1;volume 4(2):103-13.
1. Int Wound J. 2007 Jun;4(2):103-13.
A comparison of diabetic foot ulcer outcomes using negative pressure wound
therapy versus historical standard of care.
Lavery LA(1), Boulton AJ, Niezgoda JA, Sheehan P.
Author information:
(1)Texas A&M Health Science Center College of Medicine, Department of Surgery,
Scott and White Hospital, Temple, TX 78628, USA. llavery@swmail.sw.org
Diabetic foot ulcers (DFUs) are a leading cause of morbidity and hospitalisation
among patients with diabetes. We analysed claims data for Medicare part B
diabetic foot ulcer patients treated with Negative Pressure Wound Therapy at home
(N = 1135) and diabetic foot ulcer patients from a published meta-analysis of
randomised controlled wet-to-moist therapy. The expected costs of care for the
two treatments were also compared. A significantly greater proportion of wounds
treated with NPWT achieved a successful treatment endpoint compared with
wet-to-moist therapy at both 12 weeks (39.5% versus 23.9%; P < 0.001) and 20
weeks (46.3% versus 32.8%; P < 0.001). NPWT-treated patients reached a successful
wound treatment endpoint more rapidly, and the benefit was apparent in all wound
sizes. Expected 20-week treatment costs for NPWT were similar to those for
wet-to-moist therapy if one nursing visit per day for the latter is assumed but
42% less if two nursing visits per day are made. Thus, NPWT may improve the
proportion of DFUs that attain a successful wound treatment endpoint and decrease
resource utilisation by a given health care system compared with standard
wet-to-moist therapy.
DOI: 10.1111/j.1742-481X.2007.00317.x
PMID: 17651226 [Indexed for MEDLINE]
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