Löndahl M, Landin-Olsson M, Katzman P, et al.
Diabetic medicine : a journal of the British Diabetic Association. Date of publication 2011 Feb 1;volume 28(2):186-90.
1. Diabet Med. 2011 Feb;28(2):186-90. doi: 10.1111/j.1464-5491.2010.03185.x.
Hyperbaric oxygen therapy improves health-related quality of life in patients
with diabetes and chronic foot ulcer.
Löndahl M(1), Landin-Olsson M, Katzman P.
Author information:
(1)Institution for Clinical Sciences in Lund, Lund University, Lund, Sweden.
AIMS: Adjunctive treatment with hyperbaric oxygen therapy has recently been shown
to improve ulcer healing in patients with chronic diabetic foot ulcer. The aim of
the present study is to evaluate whether hyperbaric oxygen therapy improves the
health related quality of life in these patients.
METHODS: Prospective randomized placebo-controlled double-blinded study setting
using SF-36.
RESULTS: A total of 75 patients were included in the study; 38 were randomized to
hyperbaric oxygen therapy and 37 to placebo (hyperbaric air). The overall mean
physical and mental summary scores for the entire study population at baseline
were 29.6 ± 8.8 and 47.5 ± 12.4, respectively. There was a significant difference
between baseline and 1 year follow-up responses to the mental summary score and
two of the eight (SF-36) (?) domains in the -hyperbaric oxygen group, whereas no
significant improvement of health related quality of life was seen in the placebo
group. Comparing quality of life in patients who healed their ulcer (healers)
with those who did not (non-healers), post-treatment levels of the mental health
summary score, social functioning and role limitations due to physical and
emotional health were significantly improved in healers. No differences were seen
in any SF-36 (?) domain in non-healers.
CONCLUSIONS: Hyperbaric oxygen therapy improves long-term health related quality
of life in patients with chronic diabetic foot ulcers, possibly attributable to
better ulcer healing.
© 2011 The Authors. Diabetic Medicine © 2011 Diabetes UK.
DOI: 10.1111/j.1464-5491.2010.03185.x
PMID: 21219427 [Indexed for MEDLINE]
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