Hickey S, Whitson A, Jones L, Wibbenmeyer L, Ryan C, Fey R, Litt J, Fabia R, Cancio L, Mohr W, Twomey J, Wagner A, Cochran A, Bailey JK, et al.
Journal of burn care & research : official publication of the American Burn Association. Date of publication 2020 Jan 30;volume 41(1):176-183.
1. J Burn Care Res. 2020 Jan 30;41(1):176-183. doi: 10.1093/jbcr/irz148.
Guidelines for Thrombolytic Therapy for Frostbite.
Hickey S(1), Whitson A(2), Jones L(2), Wibbenmeyer L(3), Ryan C(4), Fey R(5),
Litt J(6), Fabia R(7), Cancio L(8), Mohr W(9)(10), Twomey J(11), Wagner A(12),
Cochran A(2), Bailey JK(13).
Author information:
(1)Massachusetts General Hospital, Harvard Medical School, Boston,
Massachusetts.
(2)Department of Surgery, The Ohio State University, Columbus, Ohio.
(3)Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City.
(4)Department of Surgery, Massachusetts General Hospital, Harvard Medical School
Shriners Hospitals for Children-Boston.
(5)Department of Surgery, Hennepin County Medical Center, Minneapolis Minnesota.
(6)Department of Surgery, University of Missouri School of Medicine, Columbia,
Missouri.
(7)Department of Pediatric Surgery, Nationwide Childrens Hospital, Columbus,
Ohio.
(8)United States Army Institute of Surgical Research, Fort Sam Houston, Texas.
(9)Burn Center and Department of Trauma and General Surgery, Regions Hospital,
St. Paul, Minnesota.
(10)Department of Surgery, University of Minnesota, Minneapolis.
(11)Department of Surgey, Hennepin County Medical Center, Minneapolis,
Minnesota.
(12)Department of Surgery, University of Colorado School of Medicine, Aurora,
Colorado.
(13)Department of Surgery, Wake Forest University School of Medicine, Medical
Center Blvd, Winston-Salem, North Carolina.
Comment in
J Burn Care Res. 2020 Jul 3;41(4):919. doi: 10.1093/jbcr/iraa046.
The data are insufficient to support standardized treatment of all patients with
frostbite with thrombolytic therapy. The following guidelines, however, should
be applied to all patients with cyanosis persisting proximal to the distal
phalanx (Grade 3 or 4 frostbite injury) and demonstrated loss of perfusion at or
proximal to the middle phalanx immediately after rewarming.
© American Burn Association 2020. All rights reserved. For permissions, please
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DOI: 10.1093/jbcr/irz148
PMID: 31899512 [Indexed for MEDLINE]