Madero J, Salvador M, Kadouch J, Muñoz-Gonzalez C, Fakih-Gomez N, et al.
Aesthetic plastic surgery. Date of publication 2024 Jul 1;volume 48(14):2713-2721.
1. Aesthetic Plast Surg. 2024 Jul;48(14):2713-2721. doi:
10.1007/s00266-024-03920-7. Epub 2024 Mar 8.
Role of Hyperbaric Oxygen in Filler-Induced Vascular Occlusion.
Madero J(1), Salvador M(2), Kadouch J(3), Muñoz-Gonzalez C(4), Fakih-Gomez N(5).
Author information:
(1)Critical Care Unit, Provincial Hospital of Castellon, Castellón de la Plana,
Spain.
(2)Hyperbaric Therapy Unit, General Hospital of Castellon, Castellón de la
Plana, Spain.
(3)Practice for Aesthetic Dermatology, ReSculpt Clinic, Amsterdam, The
Netherlands.
(4)Department of Facial Plastic and Cranio-Maxillo-Facial Surgery, Fakih
Hospital, Main Street Khaizaran, Saida, Lebanon.
(5)Department of Facial Plastic and Cranio-Maxillo-Facial Surgery, Fakih
Hospital, Main Street Khaizaran, Saida, Lebanon. info@drnabilfakih.com.
INTRODUCTION: The rising incidence of filler-induced vascular complications in
the context of aesthetic procedures necessitates a thorough assessment of
therapeutic options. Hyperbaric oxygen therapy (HBOT) has emerged as a potential
intervention for filler-induced vascular occlusion (FIVO), although optimal
dosing and timing remain undefined.
METHODS: This review explores the pathophysiology of FIVO and elucidates HBOT's
multifaceted role in salvaging ischemic tissue. The physical and biochemical
mechanisms of HBOT, including its vasodilatory, anti-spasmodic, and
anti-inflammatory effects, are examined.
RESULTS: HBOT serves as an adjunctive therapy in FIVO management, emphasizing
timely intervention, adherence to specific pressures (two atmosphere absolute),
and session durations (60 minutes) to optimize efficacy and minimize
complications. While existing HBOT protocols for compromised grafts provide
insights, standardized guidelines for FIVO are lacking.
CONCLUSION: HBOT enhances tissue oxygenation, modulates reactive oxygen species,
and influences angiogenesis and hypoxia response. However, it does not replace
key treatment protocols for filler vascular complications. Further research and
standardized protocols are warranted to define HBOT's definitive role in
mitigating filler-induced vascular complications. Level of Evidence IV This
journal requires that authors assign a level of evidence to each article. For a
full description of these Evidence-Based Medicine ratings, please refer to the
Table of Contents or the online Instructions to Authors www.springer.com/00266 .
© 2024. Springer Science+Business Media, LLC, part of Springer Nature and
International Society of Aesthetic Plastic Surgery.
DOI: 10.1007/s00266-024-03920-7
PMID: 38459381 [Indexed for MEDLINE]
