Cao G, Gu HC, Wang JT, Huang Q, Cao JC, et al.
International wound journal. Date of publication 2019 Jun 1;volume 16(3):696-702.
1. Int Wound J. 2019 Jun;16(3):696-702. doi: 10.1111/iwj.13083. Epub 2019 Feb 15.
Comparison of endovenous laser treatment and high ligation in treatment of limb
varicosity: A meta-analysis.
Cao G(1), Gu HC(1), Wang JT(1), Huang Q(1), Cao JC(1).
Author information:
(1)Department of the Fourth Surgery, Dong-Fang Hospital of Beijing University of
Chinese Medicine, Beijing, China.
To assess the efficacy and safety of endovenous laser treatment (EVLT) and high
ligation (HL) for limb varicosity using meta-analysis. Multiple databases
including PubMed, Springer, Excerpta Medica Database, Ovid Technologies, and
China Journal Full-text database were searched for relevant studies in English
or Chinese, and full-text articles were used to compare EVLT and HL for limb
varicosity. Review Manager 5.0 was used to estimate the effects of the results
among eligible articles. Forest plots, sensitivity analysis, and bias analysis
of the included articles were also conducted. Initial screening yielded 1031
studies, 11 randomised controlled trials involving 1145 limb varicosity patients
met the inclusion criteria in this study. The results of the heterogeneity test
suggested that intraoperative blood loss mean difference (MD) = -6.31[-9.03,
-3.60], P < 0.00001), operative time (MD) = -39.76[-42.27, -37.24], P <
0.00001), rate of complications (odds ratio [OR] = 0.37[0.22, 0.61],
P < 0.0001), and recurrence (OR = 0.28[0.16, 0.49], P < 0.0001) were
significantly different. Although both EVLT and HL have their own merits and
demerits, EVLT is a more effective and safe method to treat limb varicosity.
© 2019 Medicalhelplines.com Inc and John Wiley & Sons Ltd.
DOI: 10.1111/iwj.13083
PMCID: PMC7949302
PMID: 30767406 [Indexed for MEDLINE]
