Jiang F, Zhang Y, Cheng S, Yang X, Bai M, Zhang M, et al.
International wound journal. Date of publication 2024 Apr 1;volume 21(4):e14530.
1. Int Wound J. 2024 Apr;21(4):e14530. doi: 10.1111/iwj.14530. Epub 2023 Dec 6.
Quality of evidence supporting the role of hyperbaric oxygen therapy for
diabetic foot ulcers.
Jiang F(1), Zhang Y(2), Cheng S(3), Yang X(3), Bai M(1), Zhang M(4).
Author information:
(1)General Medicine Department, Xigu Hospital of Lanzhou University Second
Hospital, Lanzhou, China.
(2)The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
(3)Tianjin University of Traditional Chinese Medicine, Tianjin, China.
(4)Endocrinology Department, Lanzhou University Second Hospital, Lanzhou, China.
The goal of this overview of systematic reviews (SRs) and meta-analyses (MAs)
was to methodically gather, evaluate and summarize the data supporting the use
of hyperbaric oxygen therapy (HBOT) to treat diabetic foot ulcers (DFUs). The
Cochrane Library, Embase, PubMed, Web of Science and Embase were all searched
thoroughly to identify SRs/MAs that qualified. AMSTAR-2 tool, PRISMA checklists
and GRADE system were applied by two reviewers independently to assess the
methodological quality, reporting and evidence quality of the included SRs/MAs,
respectively. Eleven SRs/MAs were enrolled in this overview. According to
AMSTAR-2, a very low methodological quality assessment was given to the included
SRs/MAs due to the limitations of items 2, 4 and 7. For the PRISMA, the overall
quality of reporting is not satisfactory due to missing reporting on protocol,
search, as well as additional analysis. The majority of outcomes had low- to
moderate-quality evidence, and no high-quality evidence was found to support the
role of HBOT for DFUs, according to GRADE. To conclude, the potential of HBOT in
treating DFUs is supported by evidence of low to moderate quality. More
rigorously designed, high-level studies are needed in the future to determine
the evidence for HBOT for DFU, including the timing, frequency and duration of
HBOT interventions.
© 2023 The Authors. International Wound Journal published by
Medicalhelplines.com Inc and John Wiley & Sons Ltd.
DOI: 10.1111/iwj.14530
PMCID: PMC10961030
PMID: 38053520 [Indexed for MEDLINE]
Conflict of interest statement: The authors declare that they have no conflicts
of interest.
