Zhou Y, Chen Y, Yin G, Xie Q, et al.
International wound journal. Date of publication 2023 Apr 1;volume 20(4):1316-1327.
1. Int Wound J. 2023 Apr;20(4):1316-1327. doi: 10.1111/iwj.13972. Epub 2022 Oct
23.
Calciphylaxis and its co-occurrence with connective tissue diseases.
Zhou Y(1), Chen Y(1), Yin G(2), Xie Q(1).
Author information:
(1)Department of Rheumatology and Immunology, West China Hospital, Sichuan
University, Chengdu, China.
(2)Department of General Practice, General Practice Medical Center, West China
Hospital, Sichuan University, Chengdu, China.
Calciphylaxis, also known as calcific uremic arteriopathy, is a rare
calcification syndrome that presents as ischemic skin necrosis and severe pain.
It has a high mortality rate and is characterised by calcification of the small
and medium arteries and micro-thrombosis. Calciphylaxis mainly occurs in
patients with end-stage renal disease. In recent years, there have been an
increasing number of cases of calciphylaxis associated with connective tissue
diseases. Given the absence of clear diagnostic criteria for calciphylaxis thus
far, an early diagnosis is crucial for designing an effective multidisciplinary
treatment plan. In this article, we review the research progress on
calciphylaxis and describe its characteristics in the context of connective
tissue diseases.
© 2022 The Authors. International Wound Journal published by
Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd.
DOI: 10.1111/iwj.13972
PMCID: PMC10031236
PMID: 36274216 [Indexed for MEDLINE]
Conflict of interest statement: The authors declare no potential conflict of
interest.
