Author(s) Patton D, Avsar P, Sayeh A, Budri A, O'Connor T, Walsh S, Nugent L, Harkin D, O'Brien N, Cayce J, Corcoran M, Gaztambide M, Moore Z, et al.

Journal International wound journal. Date of publication 2023 Feb 1;volume 20(2):430-447.

Abstract 1. Int Wound J. 2023 Feb;20(2):430-447. doi: 10.1111/iwj.13891. Epub 2022 Jul 18. A meta-review of the impact of compression therapy on venous leg ulcer healing. Patton D(1)(2)(3)(4)(5), Avsar P(1)(2), Sayeh A(1), Budri A(1)(2), O'Connor T(1)(2)(3)(4)(6), Walsh S(1), Nugent L(1)(2)(3), Harkin D(7), O'Brien N(8), Cayce J(9), Corcoran M(10), Gaztambide M(10), Moore Z(1)(2)(3)(4)(6)(11)(12)(13)(14). Author information: (1)Skin Wounds and Trauma Research Centre, The Royal College of Surgeons in Ireland (RCSI), University of Medicine and Health Sciences, Dublin, Ireland. (2)School of Nursing and Midwifery, The Royal College of Surgeons in Ireland (RCSI), University of Medicine and Health Sciences, Dublin, Ireland. (3)Fakeeh College of Medical Sciences, Jeddah, Saudi Arabia. (4)School of Nursing and Midwifery, Griffith University, Southport, Queensland, Australia. (5)Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, New South Wales, Australia. (6)Lida Institute, Shanghai, China. (7)The Royal College of Surgeons in Ireland (RCSI), University of Medicine and Health Sciences, Faculty of Medicine and Health Sciences, Dublin, Ireland. (8)The Royal College of Surgeons in Ireland (RCSI), University of Medicine and Health Sciences, Dublin, Ireland. (9)DeRoyal Industries, Knoxville, Tennessee, USA. (10)DeRoyal International, Dublin, Ireland. (11)Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia. (12)Department of Public Health, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium. (13)University of Wales, Cardiff, UK. (14)National Health and Medical Research Council Centre of Research Excellence in Wiser Wound Care, Menzies Health Institute Queensland, Southport, Queensland, Australia. This meta-review aimed to appraise and synthesise findings from existing systematic reviews that measured the impact of compression therapy on venous leg ulcers healing. We searched five databases to identify potential papers; three authors extracted data, and a fourth author adjudicated the findings. The AMSTAR-2 tool was used for quality appraisal and the certainty of the evidence was appraised using GRADEpro. Data analysis was undertaken using RevMan. We identified 12 systematic reviews published between 1997 and 2021. AMSTAR-2 assessment identified three as high quality, five as moderate quality, and four as low quality. Seven comparisons were reported, with a meta-analysis undertaken for five of these comparisons: compression vs no compression (risk ratio [RR]: 1.55; 95% confidence interval [CI] 1.34-1.78; P < .00001; moderate-certainty evidence); elastic compression vs inelastic compression (RR: 1.02; 95% CI: 0.96-1.08; P < .61 moderate-certainty evidence); four layer vs

Source ID (e.g. PMID): 35855678

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