Rogan S, Taeymans J, Luginbuehl H, Aebi M, Mahnig S, Gebruers N, et al.
Breast cancer research and treatment. Date of publication 2016 Aug 1;volume 159(1):1-14.
1. Breast Cancer Res Treat. 2016 Aug;159(1):1-14. doi: 10.1007/s10549-016-3919-4.
Epub 2016 Jul 26.
Therapy modalities to reduce lymphoedema in female breast cancer patients: a
systematic review and meta-analysis.
Rogan S(1)(2), Taeymans J(3)(4), Luginbuehl H(3), Aebi M(3), Mahnig S(3),
Gebruers N(5).
Author information:
(1)Discipline of Physiotherapy, Bern University of Applied Sciences, Bern,
Switzerland. slavko.rogan@bfh.ch.
(2)Academy of integrative Physiotherapy and Training Education, Grenzach-Wyhlen,
Germany. slavko.rogan@bfh.ch.
(3)Discipline of Physiotherapy, Bern University of Applied Sciences, Bern,
Switzerland.
(4)Faculty for Sports and Rehabilitation Science, Vrije Universiteit Brussel,
Brussels, Belgium.
(5)Rehabilitation Sciences & Physiotherapy, University of Antwerp, Antwerp,
Belgium.
The aim of the present study was to evaluate the effects of compression bandages,
sleeves, intermittent pneumatic compression (IPC) and active exercise on the
reduction of breast cancer-related lymphoedema (BCRL). A systematic literature
search up to the year January 2016 was performed in CINAHL, Cochrane Register of
Controlled Trials, Embase, International Clinical Trials Registry Platform (WHO),
PEDro and PubMed. Inclusion criteria were (1) RCTs, (2) reported adequate
statistics for meta-analysis, (3) English or German language. Exclusion criteria
were (1) effects of drugs, hormonal, radiation and surgical procedures, (2)
studies with children, (3) non-breast cancers, lower extremity oedema, (4) impact
on fatigue only, diets or sexually transmitted diseases, (5) cost-analysis only
and (6) non-carcinogenic syndromes or (7) prevention of breast cancer. After
scoring the methodological quality of the selected studies, data concerning
volume reduction of the oedema swelling were extracted. Thirty-two studies were
included in this systematic review. Nine studies were selected for the RCT-based
studies and 19 studies were included in the pre-post studies-based random-effects
meta-analyses. All conclusions should be taken with precautions because of the
insufficient quality of the selected papers. Exercise seems beneficial in
reducing oedema volume in BCRL. IPC seems beneficial in helping to reduce the
oedema volume in the acute phase of treatment. Compression sleeves do not aid in
the volume reduction in the acute phase; however, they do prevent additional
swelling.
DOI: 10.1007/s10549-016-3919-4
PMID: 27460637 [Indexed for MEDLINE]
