Janowska A, Dini V, Oranges T, Iannone M, Loggini B, Romanelli M, et al.
Clinical interventions in aging. Date of publication 2019 Dec 10;volume 14():2137-2143.
1. Clin Interv Aging. 2019 Dec 10;14:2137-2143. doi: 10.2147/CIA.S231896.
eCollection 2019.
Atypical Ulcers: Diagnosis and Management.
Janowska A(1), Dini V(1), Oranges T(1)(2), Iannone M(1), Loggini B(3), Romanelli
M(1).
Author information:
(1)Department of Dermatology, University of Pisa, Pisa, Italy.
(2)Department of Health Sciences, Anna Meyer Children University Hospital,
University of Florence, Florence, Italy.
(3)Department of Pathology, University of Pisa, Pisa, Italy.
Atypical ulcers show atypical clinical features, histology, localization, and
resistance to standard therapies. The persistence of a chronic ulcer despite
treatment with standard therapies requires a more specific diagnostic
investigation. Diagnosis involves obtaining the history and performing clinical
examination and additional tests. A skin biopsy is frequently used to confirm
unclear diagnosis. In difficult cases, microbiological and immunohistochemical
examinations, laboratory blood tests, or instrumental tests should be evaluated.
The treatment of atypical wounds is characterized by local systemic therapy and
pain control. Our results highlight the need for early diagnosis, and
standardized and targeted management by a multidisciplinary wound healing center.
© 2019 Janowska et al.
DOI: 10.2147/CIA.S231896
PMCID: PMC6911347
PMID: 31849457 [Indexed for MEDLINE]
Conflict of interest statement: The authors report no conflicts of interest in
this work.
