Lentz R, Shin C, Bloom Z, Yamada K, Hong YK, Wong AK, Patel K, et al.
Lymphatic research and biology. Date of publication 2021 Feb 1;volume 19(1):11-16.
1. Lymphat Res Biol. 2021 Feb;19(1):11-16. doi: 10.1089/lrb.2020.0118. Epub 2021 Feb
5.
From Bench to Bedside: The Role of a Multidisciplinary Approach to Treating
Patients with Lymphedema.
Lentz R(1), Shin C(1), Bloom Z(1), Yamada K(1), Hong YK(1), Wong AK(1), Patel
K(1).
Author information:
(1)Division of Plastic and Reconstructive Surgery, Department of Surgery,
University of Southern California, Los Angeles, California, USA.
Background: Lymphedema is a condition characterized by dysfunction of the
lymphatic system resulting in chronic, progressive soft tissue edema that can
negatively impact individuals' function, self-image, and quality of life.
Understanding of the disease process has evolved significantly in the past two
decades with advances in diagnostic modalities and surgical techniques
revolutionizing prior treatment algorithms. Methods and Results: We reviewed our
current approach at the University of Southern California to improving outcomes
in lymphedema treatment. Given the complexity of this medical condition, patients
are best served by a multidisciplinary approach. At our institution, this
involves a collaborative effort between bench researchers, lymphatic therapists,
medical physicians, and lymphedema surgeons. Basic science and translational
research provide further understanding into the underlying mechanisms of
lymphangiogenesis and the possibility for potential therapeutic interventions.
Our surgical algorithms require patients to undergo a thorough diagnostic
evaluation and consultation with certified lymphatic therapists prior to
undergoing either physiologic or debulking operations. Patients are followed
clinically following any interventions. Further community outreach and education
is carried out in order to improve upon early diagnosis and symptom recognition.
Conclusions: Optimizing lymphedema care requires a collaborative interplay
between researchers, physicians, and therapists. Additionally, patient and
provider education on early disease recognition and treatment options is an
equally critical aspect of improving patient outcomes.
DOI: 10.1089/lrb.2020.0118
PMCID: PMC8020565 [Available on 2022-02-01]
PMID: 33544026 [Indexed for MEDLINE]
