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Trevor LV, Riches-Suman K, Mahajan AL, Thornton MJ, et al.
Journal of clinical medicine. Date of publication 2020 Jul 8;volume 9(7):.
1. J Clin Med. 2020 Jul 8;9(7). pii: E2161. doi: 10.3390/jcm9072161. Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing. Trevor LV(1)(2), Riches-Suman K(3), Mahajan AL(1)(2), Thornton MJ(1)(3). Author information: (1)Plastic Surgery and Burns Research Unit, University of Bradford, Bradford BD71DP, UK. (2)Department of Plastic and Reconstructive Surgery, Bradford Teaching Hospitals NHS Foundation Trust, Bradford BD71DP, UK. (3)Centre for Skin Sciences, Faculty of Life Sciences, University of Bradford, Bradford BD71DP, UK. Interest in adipose tissue is fast becoming a focus of research after many years of being considered as a simple connective tissue. It is becoming increasingly apparent that adipose tissue contains a number of diverse cell types, including adipose-derived stem cells (ASCs) with the potential to differentiate into a number of cell lineages, and thus has significant potential for developing therapies for regenerative medicine. Currently, there is no gold standard treatment for scars and impaired wound healing continues to be a challenge faced by clinicians worldwide. This review describes the current understanding of the origin, different types, anatomical location, and genetics of adipose tissue before discussing the properties of ASCs and their promising applications for tissue engineering, scarring, and wound healing. DOI: 10.3390/jcm9072161 PMCID: PMC7408846 PMID: 32650555
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