Poku E, Duncan R, Keetharuth A, Essat M, Phillips P, Woods HB, Palfreyman S, Jones G, Kaltenthaler E, Michaels J, et al.
Health and quality of life outcomes. Date of publication 2016 Nov 24;volume 14(1):161.
1. Health Qual Life Outcomes. 2016 Nov 24;14(1):161.
Patient-reported outcome measures in patients with peripheral arterial disease: a
systematic review of psychometric properties.
Poku E(1), Duncan R(2), Keetharuth A(2), Essat M(2), Phillips P(2), Woods HB(2),
Palfreyman S(3), Jones G(4), Kaltenthaler E(2), Michaels J(2).
Author information:
(1)School of Health and Related Research, University of Sheffield, Sheffield, S1
4DA, UK. e.poku@sheffield.ac.uk.
(2)School of Health and Related Research, University of Sheffield, Sheffield, S1
4DA, UK.
(3)University of Alberta, 116 St & 85 Ave, Edmonton, T6G 2R3, AB, Canada.
(4)Leeds Beckett University, School of Social Sciences, City Campus, Leeds, LS1
3HE, UK.
BACKGROUND: Peripheral arterial disease (PAD) is generally associated with
considerable morbidity and reduced quality of life. Patient-reported outcome
measures (PROMs) provide important information about the burden of disease and
impact of treatment in affected patients.
OBJECTIVES: The objective of the review was to identify and appraise studies
reporting the psychometric evaluation of PROMs administered to a specified
population of patients with PAD with a view to recommending suitable PROMs.
METHODS: A systematic review of peer-reviewed English language articles was
undertaken to identify primary studies reporting psychometric properties of PROMs
in English-speaking patients with various stages of PAD. Comprehensive searches
were completed up until January 2015. Study selection, data extraction and
quality assessment were undertaken independently by at least two researchers.
Findings were presented as tabular and narrative summaries based on accepted
guidance.
RESULTS: Psychometric evaluation of 6 generic and 7 condition-specific PROMs
reported in 14 studies contributed data to the review. The frequently reported
measure was the SF-36 (n = 11 studies); others included the Walking Impairment
Questionnaire (n = 8 studies), EQ-5D (n = 5 studies) and the Vascular Quality of
Life Questionnaire (n = 3 studies). Studies included a diverse PAD population and
varied in methodology, including approach to validation of PROMs.
CONCLUSIONS: Various PROMs have been validated in patients with PAD but no study
provided evidence of a full psychometric evaluation in the patient population.
Careful selection is required to identify reliable and valid PROMs to use in
clinical and research settings.
DOI: 10.1186/s12955-016-0563-y
PMCID: PMC5121983
PMID: 27881127 [Indexed for MEDLINE]
