Karadsheh M, Nelson J, Rechner B, Wilcox R, et al.
Wounds : a compendium of clinical research and practice. Date of publication 2017 Nov 1;volume 29(11):E106-E110.
1. Wounds. 2017 Nov;29(11):E106-E110.
Application of a Skin Adhesive to Maintain Seal in Negative Pressure Wound
Therapy: Demonstration of a New Technique.
Karadsheh M(1), Nelson J(2), Rechner B(2), Wilcox R(3).
Author information:
(1)Albert Einstein Medical Center, Philadelphia, PA; Michigan State University
College of Human Medicine, East Lansing, MI.
(2)Michigan State University College of Human Medicine, East Lansing, MI; and
Grand Rapids Medical Education Partners, Grand Rapids, MI.
(3)Michigan State University College of Human Medicine, East Lansing, MI.
Optimal wound healing with negative pressure wound therapy (NPWT) relies on a
properly sealed vacuum system. Anatomically difficult wounds impair the adhesive
dressing, which results in air leaks that disrupt the integrity of the NPWT
system and hinder wound healing.OBJECTIVE: The authors demonstrate a new
technique using a cyanoacrylate-based tissue adhesive to maintain an airtight,
durable seal in NPWT.
MATERIALS AND METHODS: A 52-year-old woman with a degloving injury to the right
thigh extending into the groin, resulting in massive necrosis, presented to the
emergency department. Using a skin closure system, 2 polyester mesh tape strips
were placed near the perineal region of the wound to reinforce the adhesive drape
of the NPWT system. Skin grafts were applied over the wound after about 3 weeks
of NPWT, and the skin closure system was applied in the same fashion to reinforce
the adhesive drape.
RESULTS: An airtight seal was consistently maintained for several days in between
dressing changes. The size of the wound was visibly reduced at each dressing
change. An airtight seal was maintained for 5 days after placement of the skin
grafts; after 5 days, the dressing was removed without difficulty and skin
irritation. The skin grafts appeared healthy with adequate tissue take.
CONCLUSIONS: Maintaining an airtight seal in NPWT is crucial to wound healing.
Cyanoacrylate tissue adhesives appear to be a safe and viable option for creating
a durable seal in NPWT for wounds in anatomically difficult locations.
PMID: 29166258 [Indexed for MEDLINE]
