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John BV, Chamilos G, Kontoyiannis DP, et al.
Clinical microbiology and infection : the official publication of the European Society of Clini.... Date of publication 2005 Jul 1;volume 11(7):515-7.
1. Clin Microbiol Infect. 2005 Jul;11(7):515-7. Hyperbaric oxygen as an adjunctive treatment for zygomycosis. John BV, Chamilos G, Kontoyiannis DP. Zygomycosis is a rare but emerging mycosis. Because of the sub-optimal efficacy of the standard antifungal treatment for this disease, hyperbaric oxygen (HBO) has been used occasionally as an adjunctive therapeutic modality. A review of 28 published cases of zygomycosis indicates that adjunctive HBO may be beneficial in diabetic patients (94% survival), whereas its benefit in the small group of patients with haematological malignancies or bone marrow transplants is doubtful (33% survival; p 0.02). Prolonged courses of HBO were associated with a higher survival (100% survival; p 0.003). Additional studies are required to assess the optimal timing and dose for HBO treatment. DOI: 10.1111/j.1469-0691.2005.01170.x PMID: 15966968 [Indexed for MEDLINE]
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Pyogenic and Invasive Fungal Intracranial Abscesses