Grainger JT, Maeda Y, Donnelly SC, Vaizey CJ, et al.
Clinical and experimental gastroenterology. Date of publication 2018 Jun 12;volume 11():233-241.
1. Clin Exp Gastroenterol. 2018 Jun 12;11:233-241. doi: 10.2147/CEG.S122868.
eCollection 2018.
Assessment and management of patients with intestinal failure: a
multidisciplinary approach.
Grainger JT(1), Maeda Y(1)(2), Donnelly SC(1), Vaizey CJ(1)(2).
Author information:
(1)The Lennard Jones Intestinal Failure Unit, St. Mark's Hospital, Harrow, UK.
(2)Faculty of Medicine, Imperial College London, London, UK.
Intestinal failure (IF) is a condition characterized by the inability to maintain
a state of adequate nutrition, or fluid and electrolyte balance due to an
anatomical or a physiological disorder of the gastrointestinal system. IF can be
an extremely debilitating condition, significantly affecting the quality of life
of those affected. The surgical management of patients with acute and chronic IF
requires a specialist team who has the expertise in terms of technical challenges
and decision-making. A dedicated IF unit will have the expertise in patient
selection for surgery, investigative workup and planning, operative risk
assessment with relevant anesthetic expertise, and a multidisciplinary team with
support such as nutritional expertise and interventional radiology. This article
covers the details of IF management, including the classification of IF,
etiology, prevention of IF, and initial management of IF, focusing on sepsis
treatment and nutritional support. It also covers the surgical aspects of IF such
as intestinal reconstruction, abdominal wall reconstruction, and intestinal
transplantation.
DOI: 10.2147/CEG.S122868
PMCID: PMC6003282
PMID: 29928141
Conflict of interest statement: Disclosure The authors report no conflicts of
interest in this work.