Brannen AL, Still J, Haynes M, Orlet H, Rosenblum F, Law E, Thompson WO, et al.
The American surgeon. Date of publication 1997 Mar 1;volume 63(3):205-8.
1. Am Surg. 1997 Mar;63(3):205-8.
A randomized prospective trial of hyperbaric oxygen in a referral burn center
population.
Brannen AL(1), Still J, Haynes M, Orlet H, Rosenblum F, Law E, Thompson WO.
Author information:
(1)Augusta Regional Medical Center, Georgia, USA.
Various studies of the effect of hyperbaric oxygen (HBO) in a wide variety of
disease entities have been carried out. In the treatment of burns, animal and
human studies have yielded somewhat contradictory results. Controlled studies in
humans are limited. A randomized study on the effect of HBO was conducted
involving 125 burn patients admitted within 24 hours of injury who were matched
by age, burn size, and presence or absence of inhalation injury. Patients in the
treatment arm received oxygen at two atmospheres of pressure for 90 minutes twice
a day for a minimum of 10 treatments and a maximum of one treatment per total
body surface per cent burn. The control group was treated in a similar fashion,
except for the absence of HBO. There were no statistically significant
differences between the two groups for the outcome measures of mortality, number
of operations, and length of stay for the survivors. In this large clinical
trial, we were unable to demonstrate any significant benefit to burn patients
from the use of HBO.
PMID: 9036884 [Indexed for MEDLINE]
