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Micheletti RG, Werth VP, et al.
Rheumatic diseases clinics of North America. Date of publication 2015 Jan 1;volume 41(1):21-32, vii.
1. Rheum Dis Clin North Am. 2015;41(1):21-32, vii. doi: 10.1016/j.rdc.2014.09.006. Small vessel vasculitis of the skin. Micheletti RG(1), Werth VP(2). Author information: (1)Departments of Dermatology and Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address: Robert.Micheletti@uphs.upenn.edu. (2)Departments of Dermatology and Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA; Departments of Dermatology and Medicine, Philadelphia Veterans Affairs Medical Center, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. Small vessel vasculitis in the skin manifests with palpable purpura on the lower extremities. This clinical presentation prompts a complete physical examination, history, and review of systems, as well as biopsies for routine processing and direct immunofluorescence to confirm the diagnosis. The presence of vasculitis in other organs, associated underlying conditions, and the severity of cutaneous manifestations dictate management. The majority of cases are self-limited, and overall the prognosis is favorable. Still, a subset of patients can have serious complications and chronic or recurrent disease. DOI: 10.1016/j.rdc.2014.09.006 PMID: 25399937 [Indexed for MEDLINE]
Appears in following Topics:
Cutaneous Vasculitis
Case: New-onset cutaneous vasculitis