Author(s) Michaëlsson G, Molin L, Ohmann S, Gip L, Lindström B, Skogh M, Trolin I, et al.

Journal Archives of dermatology. Date of publication 1976 Mar 1;volume 112(3):344-9.

Abstract 1. Arch Dermatol. 1976 Mar;112(3):344-9. Clofazimine. A new agent for the treatment of pyoderma gangrenosum. Michaëlsson G, Molin L, Ohmann S, Gip L, Lindström B, Skogh M, Trolin I. Eight patients had pyoderma gangrenosum. They were given a phendimetrazine tartrate derivative, clofazimine (Lamprene [Britain]), which is a chemotherapeutic agent used mainly in certain mycobacterial infections and which also has phagocytosis-enhancing properties. The effect of this drug was remarkably good, with rapid healing of the lesions commencing 3 to 14 days after treatment was started. The mechanism for the effect of clofazimine in pyoderma gangrenosum is not known. PMID: 1259447 [Indexed for MEDLINE]

Source ID (e.g. PMID): 1259447