Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A, et al.
CA: a cancer journal for clinicians. Date of publication 2018 Nov 1;volume 68(6):394-424.
1. CA Cancer J Clin. 2018 Nov;68(6):394-424. doi: 10.3322/caac.21492. Epub 2018 Sep
12.
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality
worldwide for 36 cancers in 185 countries.
Bray F(1), Ferlay J(2), Soerjomataram I(3), Siegel RL(4), Torre LA(5), Jemal
A(6).
Author information:
(1)Head, Section of Cancer Surveillance, International Agency for Research on
Cancer, Lyon, France.
(2)Informatics Officer, Section of Cancer Surveillance, International Agency for
Research on Cancer, Lyon, France.
(3)Deputy Head, Section of Cancer Surveillance, International Agency for Research
on Cancer, Lyon, France.
(4)Scientific Director, Surveillance and Health Services Research, American
Cancer Society, Atlanta, GA.
(5)Scientist, Surveillance and Health Services Research, American Cancer Society,
Atlanta, GA.
(6)Scientific Vice President, Surveillance and Health Services Research, American
Cancer Society, Atlanta, GA.
This article provides a status report on the global burden of cancer worldwide
using the GLOBOCAN 2018 estimates of cancer incidence and mortality produced by
the International Agency for Research on Cancer, with a focus on geographic
variability across 20 world regions. There will be an estimated 18.1 million new
cancer cases (17.0 million excluding nonmelanoma skin cancer) and 9.6 million
cancer deaths (9.5 million excluding nonmelanoma skin cancer) in 2018. In both
sexes combined, lung cancer is the most commonly diagnosed cancer (11.6% of the
total cases) and the leading cause of cancer death (18.4% of the total cancer
deaths), closely followed by female breast cancer (11.6%), prostate cancer
(7.1%), and colorectal cancer (6.1%) for incidence and colorectal cancer (9.2%),
stomach cancer (8.2%), and liver cancer (8.2%) for mortality. Lung cancer is the
most frequent cancer and the leading cause of cancer death among males, followed
by prostate and colorectal cancer (for incidence) and liver and stomach cancer
(for mortality). Among females, breast cancer is the most commonly diagnosed
cancer and the leading cause of cancer death, followed by colorectal and lung
cancer (for incidence), and vice versa (for mortality); cervical cancer ranks
fourth for both incidence and mortality. The most frequently diagnosed cancer and
the leading cause of cancer death, however, substantially vary across countries
and within each country depending on the degree of economic development and
associated social and life style factors. It is noteworthy that high-quality
cancer registry data, the basis for planning and implementing evidence-based
cancer control programs, are not available in most low- and middle-income
countries. The Global Initiative for Cancer Registry Development is an
international partnership that supports better estimation, as well as the
collection and use of local data, to prioritize and evaluate national cancer
control efforts. CA: A Cancer Journal for Clinicians 2018;0:1-31. © 2018 American
Cancer Society.
© 2018 American Cancer Society.
DOI: 10.3322/caac.21492
PMID: 30207593
