WoundReference improves clinical decisions
 Choose the role that best describes you
Sharma A, Schwartz RA, et al.
Journal of the American Academy of Dermatology. Date of publication 2012 Dec 1;volume 67(6):1342-8.
1. J Am Acad Dermatol. 2012 Dec;67(6):1342-8. doi: 10.1016/j.jaad.2012.04.028. Epub 2012 Jun 8. Stewart-Treves syndrome: pathogenesis and management. Sharma A(1), Schwartz RA. Author information: (1)Dermatology and Pathology, New Jersey Medical School, Newark, New Jersey 07103-2714, USA. Stewart-Treves syndrome is a malignancy that arises within chronic lymphedema. Although classically described as a consequence of radical mastectomy, this lymphangiosarcoma has been documented to occur in cases of congenital and other causes of chronic secondary lymphedema. The development of this aggressive lymphangiosarcoma at sites of chronic lymphedema renders it a possible model for Kaposi sarcoma. Because of the increase in conservative treatment for breast carcinoma and improvement of operative and radiation therapy techniques, the prevalence of Stewart-Treves syndrome has decreased. Regardless, this malignancy significantly worsens patients' outcomes and needs to be diagnosed and treated early. Chemotherapy and radiation therapy have not improved survivorship significantly. Early amputation or wide local excision offers the best chance for long-term survival. Yet, overall prognosis remains dismal. Untreated patients usually live 5 to 8 months after diagnosis. Copyright © 2012 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved. DOI: 10.1016/j.jaad.2012.04.028 PMID: 22682884 [Indexed for MEDLINE]
Appears in following Topics:
Lymphedema - Introduction and Assessment
Lymphedema - Treatment and Emerging Strategies for Prevention