Diaz D, Lafontant A, Neidrauer M, Weingarten MS, DiMaria-Ghalili RA, Scruggs E, Rece J, Fried GW, Kuzmin VL, Zubkov L, et al.
Journal of biomedical optics. Date of publication 2017 Feb 1;volume 22(2):25003.
1. J Biomed Opt. 2017 Feb 1;22(2):25003. doi: 10.1117/1.JBO.22.2.025003.
Pressure injury prediction using diffusely scattered light.
Diaz D(1), Lafontant A(1), Neidrauer M(1), Weingarten MS(2), DiMaria-Ghalili
RA(3), Scruggs E(4), Rece J(4), Fried GW(4), Kuzmin VL(5), Zubkov L(1).
Author information:
(1)Drexel University, School of Biomedical Engineering, Philadelphia,
Pennsylvania, United States.
(2)Drexel University, College of Medicine, Department of Surgery, Philadelphia,
Pennsylvania, United States.
(3)Drexel University, College of Nursing and Health Professions, Philadelphia,
Pennsylvania, United States.
(4)Magee Rehabilitation Hospital, Philadelphia, Pennsylvania, United States.
(5)St. Petersburg Polytechnic University, Saint Petersburg, Russia.
Pressure injuries (PIs) originate beneath the surface of the skin at the
interface between bone and soft tissue. We used diffuse correlation spectroscopy
(DCS) and diffuse near-infrared spectroscopy (DNIRS) to predict the development
of PIs by measuring dermal and subcutaneous red cell motion and optical
absorption and scattering properties in 11 spinal cord injury subjects with only
nonbleachable redness in the sacrococcygeal area in a rehabilitation hospital and
20 healthy volunteers. A custom optical probe was developed to obtain continuous
DCS and DNIRS data from sacrococcygeal tissue while the subjects were placed in
supine and lateral positions to apply pressure from body weight and to release
pressure, respectively. Rehabilitation patients were measured up to four times
over a two-week period. Three rehabilitation patients developed open PIs (POs)
within four weeks and eight patients did not (PNOs). Temporal correlation
functions in the area of redness were significantly different ( p < 0.01 ) during
both baseline and applied pressure stages for POs and PNOs. The results show that
our optical method may be used for the early prediction of ulcer progression.
DOI: 10.1117/1.JBO.22.2.025003
PMID: 28301656 [Indexed for MEDLINE]
