Machado RS, Viana S, Sbruzzi G, et al.
Lasers in medical science. Date of publication 2017 May 1;volume 32(4):937-944.
1. Lasers Med Sci. 2017 May;32(4):937-944. doi: 10.1007/s10103-017-2150-9. Epub 2017
Jan 23.
Low-level laser therapy in the treatment of pressure ulcers: systematic review.
Machado RS(1), Viana S(2), Sbruzzi G(3).
Author information:
(1)Posgraduate Program Ciências do Movimento Humano of Universidade Federal do
Rio Grande do Sul, Porto Alegre, RS, Brazil.
(2), Porto Alegre, RS, Brazil.
(3)Posgraduate Program Ciências do Movimento Humano of Universidade Federal do
Rio Grande do Sul, Porto Alegre, RS, Brazil. graciele.sbruzzi@ufrgs.br.
The aim of this study was to evaluate the effects of low-level laser therapy
(LLT) in pressure ulcers (PU) in humans through a systematic review of randomized
studies. The search includes the databases MEDLINE, PEDro, Cochrane CENTRAL, and
Lilacs, as well a manual search until May, 2016. This included randomized
clinical trials of LLT compared with other interventions, different types of LLT,
LLT placebo, or control in the treatment of PU. The outcomes evaluated were the
ulcer area, healing rate, and overall healing rate. The risk of bias was
evaluated using the tool of the Cochrane Collaboration, and the results were
analyzed descriptively. From the 386 articles identified, only four studies were
included, with two LLT used with single wavelength (1: 904 nm vs. control and 2:
940 nm vs. 808 nm vs. 658 nm vs. placebo) and two LLT used to probe cluster. One
study compared to different single wavelengths showed a significant 71% reduction
of the PU and an improved healing rate in which 47% of PU healed completely after
1 month of therapy with the use of LLT with a wavelength of 658 nm compared with
other lengths. The other analyzed wavelengths were not significant in the
assessed outcomes. Significant results were observed in the use of LLT with a
658 nm wavelength, and no evidence was found for use of wavelengths above that
for the treatment of PU. Therefore, we also found no evidence in the laser used
to probe the cluster.Registration number: CRD42016036648.
DOI: 10.1007/s10103-017-2150-9
PMID: 28116536 [Indexed for MEDLINE]