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Dwivedi MK, Srivastava RN, Bhagat AK, Agarwal R, Baghel K, Jain A, Raj S, et al.
Journal of wound care. Date of publication 2016 Apr 1;volume 25(4):199-200, 202-4, 206-7.
1. J Wound Care. 2016 Apr;25(4):199-200, 202-4, 206-7. doi: 10.12968/jowc.2016.25.4.199. Pressure ulcer management in paraplegic patients with a novel negative pressure device: a randomised controlled trial. Dwivedi MK(1), Srivastava RN(1), Bhagat AK(2), Agarwal R(3), Baghel K(1), Jain A(4), Raj S(5). Author information: (1)Department of Orthopaedic Surgery, King George's Medical University, Lucknow, U.P., India. (2)Department of Surgical Gastroenterology, King George's Medical University, Lucknow, U.P., India. (3)Sanjai Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Lucknow, India. (4)Department of Microbiology, King George's Medical University, Lucknow, U.P., India. (5)MS Ramiyah Medical College, Bangalore, India. OBJECTIVE: A randomised controlled trial to compare negative pressure wound therapy (NPWT) using our innovative negative pressure device (NPD) and the standard pressure ulcer (PU) wound dressing of in traumatic paraplegia patients. METHOD: This study was conducted in the Department of Orthopaedic Surgery at King George's Medical University, Lucknow, India. Traumatic paraplegia patients with sacral pressure ulcers of stage 3 and 4 were randomised into two groups, receiving either standard wound dressings or NPWT with NPD. The outcomes monitored were length, width (surface area), depth of PU, exudates, discharge, tissue type (necrotic, slough and red granulating tissue), and cost-effectiveness during 0 to 9 weeks follow-up. RESULTS: Length and width were significantly (p<0.01) decreased in NPWT group as compared with standard care group at week 9. At weeks 1, 2 and 3, depth was significantly (p<0.05) higher in NPWT group, whereas at week 9 a significant reduction (p=0.01) was observed. Exudates were significantly (p=0.001) lower in NPWT group at weeks 4 and 9. Conversion of slough into red granulation tissue was significantly higher in NPWT group (p=0.001). Discharge became significantly (p=0.001) lower in NPWT at week 2 and no discharge was observed after week 6. In all parameters, decrease was larger in NPWT group compared with standard care, which was significant for exudates type (p=0.03) and tissue type (p=0.004). CONCLUSION: Our NPD is better than standard wound care procedures and cost-effective for management of PU. DOI: 10.12968/jowc.2016.25.4.199 PMID: 27064369 [Indexed for MEDLINE]
Appears in following Topics:
Cellular and/or Tissue Based Products
Pressure Ulcers/Injuries - Treatment
Negative Pressure Wound Therapy