Dwivedi MK, Srivastava RN, Bhagat AK, Agarwal R, Baghel K, Jain A, Raj S, et al.
Journal of wound care. Date of publication 2016 Apr 1;volume 25(4):199-200, 202-4, 206-7.
1. J Wound Care. 2016 Apr;25(4):199-200, 202-4, 206-7. doi:
10.12968/jowc.2016.25.4.199.
Pressure ulcer management in paraplegic patients with a novel negative pressure
device: a randomised controlled trial.
Dwivedi MK(1), Srivastava RN(1), Bhagat AK(2), Agarwal R(3), Baghel K(1), Jain
A(4), Raj S(5).
Author information:
(1)Department of Orthopaedic Surgery, King George's Medical University, Lucknow,
U.P., India.
(2)Department of Surgical Gastroenterology, King George's Medical University,
Lucknow, U.P., India.
(3)Sanjai Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Lucknow,
India.
(4)Department of Microbiology, King George's Medical University, Lucknow, U.P.,
India.
(5)MS Ramiyah Medical College, Bangalore, India.
OBJECTIVE: A randomised controlled trial to compare negative pressure wound
therapy (NPWT) using our innovative negative pressure device (NPD) and the
standard pressure ulcer (PU) wound dressing of in traumatic paraplegia patients.
METHOD: This study was conducted in the Department of Orthopaedic Surgery at King
George's Medical University, Lucknow, India. Traumatic paraplegia patients with
sacral pressure ulcers of stage 3 and 4 were randomised into two groups,
receiving either standard wound dressings or NPWT with NPD. The outcomes
monitored were length, width (surface area), depth of PU, exudates, discharge,
tissue type (necrotic, slough and red granulating tissue), and cost-effectiveness
during 0 to 9 weeks follow-up.
RESULTS: Length and width were significantly (p<0.01) decreased in NPWT group as
compared with standard care group at week 9. At weeks 1, 2 and 3, depth was
significantly (p<0.05) higher in NPWT group, whereas at week 9 a significant
reduction (p=0.01) was observed. Exudates were significantly (p=0.001) lower in
NPWT group at weeks 4 and 9. Conversion of slough into red granulation tissue was
significantly higher in NPWT group (p=0.001). Discharge became significantly
(p=0.001) lower in NPWT at week 2 and no discharge was observed after week 6. In
all parameters, decrease was larger in NPWT group compared with standard care,
which was significant for exudates type (p=0.03) and tissue type (p=0.004).
CONCLUSION: Our NPD is better than standard wound care procedures and
cost-effective for management of PU.
DOI: 10.12968/jowc.2016.25.4.199
PMID: 27064369 [Indexed for MEDLINE]
