Erdoğan A, Düzgün AP, Erdoğan K, Özkan MB, Coşkun F, et al.
The Journal of foot and ankle surgery : official publication of the American College of Foot an.... Date of publication 2018 Jan 1;volume 57(6):1115-1119.
1. J Foot Ankle Surg. 2018 Nov - Dec;57(6):1115-1119. doi:
10.1053/j.jfas.2018.05.011.
Efficacy of Hyperbaric Oxygen Therapy in Diabetic Foot Ulcers Based on Wagner
Classification.
Erdoğan A(1), Düzgün AP(2), Erdoğan K(3), Özkan MB(4), Coşkun F(2).
Author information:
(1)Medical Doctor, Department of General Surgery, Ankara Numune Training and
Research Hospital, Ankara, Turkey. Electronic address: erdogannumune@hotmail.com.
(2)Medical Doctor and Professor, Department of General Surgery, Ankara Numune
Training and Research Hospital, Ankara, Turkey.
(3)Medical Doctor, Department of Internal Medicine, Ankara Numune Training and
Research Hospital, Ankara, Turkey.
(4)Medical Doctor, Department of General Surgery, Ankara Numune Training and
Research Hospital, Ankara, Turkey.
Diabetic foot ulcer is a common chronic complication of diabetes mellitus. In
addition to conventional primary therapy, there are adjuvant therapy methods such
as hyperbaric oxygen therapy for the healing of diabetic foot ulcer wounds. The
present study aimed to determine the efficacy of hyperbaric oxygen therapy in
diabetic foot ulcers based on Wagner classification. It was performed
retrospectively from prospectively collected data. One hundred thirty patients
with diabetic foot ulcers were assessed in 2 groups: 1 group received hyperbaric
oxygen therapy; the other group did not. Patients were examined according to age,
sex, ulcer grade based on Wagner classification; ulcer healing status; whether
hyperbaric oxygen therapy was received; duration of diabetes in years; HbA1C,
sedimentation, C-reactive protein levels; and presence of accompanying diseases,
including peripheral arterial disease, chronic obstructive pulmonary disease,
hypertension, chronic kidney disease, neuropathy, and retinopathy. The mean
follow-up period was 19.5 ± 4.45 months (range 12 to 28 months). Seventy-one
(54.6%) patients received hyperbaric oxygen therapy, and 59 (45.4%) patients did
not. All patients in Wagner grade 2 healed in both groups. In the group that
received hyperbaric oxygen therapy for grade 3 and 4 patients, 35 (87.5%) and 11
(84.6%) healed, respectively. In total, 60 (84.5%) patients in the group that
received hyperbaric oxygen therapy healed. The subgroup comparison conducted
according to Wagner classification revealed no differences between the 2 groups
of grades 2 and 5 patients. It also revealed that treatment had higher levels of
efficacy in the healing of ulcers in grade 3 and 4 patients.
Copyright © 2018. Published by Elsevier Inc.
DOI: 10.1053/j.jfas.2018.05.011
PMID: 30368425
