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Shin JY, Roh SG, Lee NH, Yang KM, et al.
The international journal of lower extremity wounds. Date of publication 2017 Mar 1;volume 16(1):14-22.
1. Int J Low Extrem Wounds. 2017 Mar;16(1):14-22. doi: 10.1177/1534734617699318. Influence of Epidemiologic and Patient Behavior-Related Predictors on Amputation Rates in Diabetic Patients: Systematic Review and Meta-Analysis. Shin JY(1)(2), Roh SG(1)(2), Lee NH(1)(2), Yang KM(1)(2). Author information: (1)1 Medical School of Chonbuk National University, Jeonju, Republic of Korea. (2)2 Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Republic of Korea. Amputation of patients with diabetic foot is a major issue worldwide, particularly from a medical and economic standpoint. This meta-analysis aimed to identify significant risk factors of high amputation rate among epidemiologic and patient behavior-related predictors in diabetic patients. A systematic literature review and meta-analysis were performed using MEDLINE, EMBASE, and Cochrane databases. Seven variables were extracted from the included studies and evaluated based on amputation rate. The Newcastle-Ottawa scale was used to assess the quality of the studies. The search strategy identified 101 publications. After screening, 33 articles were selected for review. Male sex and smoking were identified as significant risk factors of high amputation rate of diabetic foot. Although further investigation of long-term and randomized controlled studies is needed, we identified 2 variables as significant risk factors for high amputation rate in diabetic patients in this meta-analysis. DOI: 10.1177/1534734617699318 PMID: 28682679 [Indexed for MEDLINE]
Appears in following Topics:
Diabetic Foot Ulcer - Introduction and Assessment