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Shin JY, Roh SG, Sharaf B, Lee NH, et al.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS. Date of publication 2017 Dec 1;volume 70(12):1681-1688.
1. J Plast Reconstr Aesthet Surg. 2017 Dec;70(12):1681-1688. doi: 10.1016/j.bjps.2017.07.015. Epub 2017 Aug 5. Risk of major limb amputation in diabetic foot ulcer and accompanying disease: A meta-analysis. Shin JY(1), Roh SG(2), Sharaf B(3), Lee NH(1). Author information: (1)Department of Plastic and Reconstructive Surgery, Medical School of Chonbuk National University, Jeonju, Republic of Korea; Research Institute of Clinical Medicine-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Republic of Korea. (2)Department of Plastic and Reconstructive Surgery, Medical School of Chonbuk National University, Jeonju, Republic of Korea; Research Institute of Clinical Medicine-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Republic of Korea; Division of Plastic Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA. Electronic address: pssroh@jbnu.ac.kr. (3)Division of Plastic Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA. BACKGROUND: Limb amputation in diabetic patients raises important issues regarding low quality of life and survival rates. This meta-analysis aimed to identify predictive factors accompanying diseases with high major amputation rates in diabetic patients. METHODS: A systematic literature review and meta-analysis were performed using MEDLINE, EMBASE and Cochrane databases. Eight variables were extracted from the included studies and evaluated according to major amputation rates. The Newcastle-Ottawa scale (NOS) was utilized to assess the quality of the studies. RESULTS: The search strategy identified 101 publications. After screening, 10 articles were selected for review. Hypertension, ischemic heart disease, cerebrovascular disease, and peripheral vascular disease were identified as predictive variables of higher major amputation rates. CONCLUSIONS: Although further investigation of long-term and prospective studies is needed, we identified four variables as predisposing factors for higher major amputation in diabetic patients through meta-analysis. Copyright © 2017 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved. DOI: 10.1016/j.bjps.2017.07.015 PMID: 28865989 [Indexed for MEDLINE]
Appears in following Topics:
Diabetic Foot Ulcer - Introduction and Assessment