Gouin JP, Kiecolt-Glaser JK, et al.
Immunology and allergy clinics of North America. Date of publication 2011 Feb 1;volume 31(1):81-93.
1. Immunol Allergy Clin North Am. 2011 Feb;31(1):81-93. doi:
10.1016/j.iac.2010.09.010.
The impact of psychological stress on wound healing: methods and mechanisms.
Gouin JP(1), Kiecolt-Glaser JK.
Author information:
(1)Department of Psychology, The Ohio State University, 225 Psychology Building,
1835 Neil Avenue, Columbus, OH 43210, USA. Gouin.1@osu.edu
Comment in
Crit Care Nurs Clin North Am. 2012 Jun;24(2):201-13.
Converging and replicated evidence indicates that psychological stress can
modulate wound-healing processes. This article reviews the methods and findings
of experimental models of wound healing. Psychological stress can have a
substantial and clinically relevant impact on wound repair. Physiologic stress
responses can directly influence wound-healing processes. Furthermore,
psychological stress can indirectly modulate the repair process by promoting the
adoption of health-damaging behaviors. Translational work is needed to develop
innovative treatments able to attenuate stress-induced delays in wound healing.
Copyright © 2011 Elsevier Inc. All rights reserved.
DOI: 10.1016/j.iac.2010.09.010
PMCID: PMC3052954
PMID: 21094925 [Indexed for MEDLINE]
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