Vinceneux Talvande B, Carvalho Lallement P, Safa G, Journet Tollhupp J, Lembelembe JP, Blaise S, Maillard H, et al.
International wound journal. Date of publication 2018 Aug 9;volume ():.
1. Int Wound J. 2018 Aug 9. doi: 10.1111/iwj.12966. [Epub ahead of print]
Use of Cellutome for the healing of venous or mixed ulcers.
Vinceneux Talvande B(1), Carvalho Lallement P(2), Safa G(3), Journet Tollhupp
J(4), Lembelembe JP(5), Blaise S(6), Maillard H(1).
Author information:
(1)Service de Dermatologie du CH du Mans, Le Mans, France.
(2)Service de Dermatologie du CHU de Rouen, Rouen, France.
(3)Service de Dermatologie du CH de St Brieuc, Saint Brieuc, France.
(4)Service de Dermatologie du CH de Chalon sur Saône, Chalon sur Saône, France.
(5)Clinique des Augustines à Malestroit, Malestroit, France.
(6)Service de Médecine vasculaire La Tronche, La Tronche, France.
Venous or mixed ulcers are common and invalidating. Cutaneous transplants may be
necessary if conventional treatment is ineffective. We evaluated the performance
of Cellutome in promoting the healing of venous or mixed ulcers 2 months after
grafting. This was a retrospective, multi-centric, descriptive study of patients
who had a venous or mixed ulcer for at least several months and who received an
autologous skin graft using the Cellutome system at least 2 months before. The
principle evaluation criterion was the state of the wound after 2 months
(completely healed vs not healed). The secondary evaluation criterion was the
percentage of wound healing after 2 months. A total of 47 patients were included
in the study. The ulcers had evolved over an average of 18 months. The average
surface area was 13.37 cm2 . After 2 months, the grafts of 26 of 47 patients
(55.3%) were completely healed. The grafts of 21 patients (44.6%) were not
completely healed but showed an average rate of healing of 51%. Use of the
Cellutome system for epidermal transplants promoted complete or improved healing
after 2 months for 55.3% of patients with chronic venous or mixed ulcers. The
limited data on the rate of healing of conventional transplants in the literature
report rates of approximately 50%. The Cellutome system may therefore be of
interest as the healing rate is similar to that of conventional techniques, but
using a much simpler, painless procedure on an outpatient basis.
© 2018 Medicalhelplines.com Inc and John Wiley & Sons Ltd.
DOI: 10.1111/iwj.12966
PMID: 30091520
