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Castro DL, Santos VL, et al.
Revista da Escola de Enfermagem da U S P. Date of publication 2015 Oct 1;volume 49(5):858-63.
1. Rev Esc Enferm USP. 2015 Oct;49(5):858-63. doi: 10.1590/S0080-623420150000500021. [Controlling wound odor with metronidazole: a systematic review]. [Article in Portuguese] Castro DL(1), Santos VL(2). Author information: (1)Escola de Enfermagem, Universidade de São Paulo, São Paulo, SP, Brazil. (2)Departamento de Enfermagem Médico-Cirúrgica, Escola de Enfermagem, Universidade de São Paulo, São Paulo, SP, Brazil. OBJECTIVE: Verifying the evidence of therapeutic efficacy in the topical application of metronidazole for controlling wound odor. METHODS: A systematic literature review, according to the Cochrane Collaboration recommendations. RESULTS: 329 articles were identified in the Cochrane, LILACS, SciELO, CINAHL and PubMed databases, with 14 of them being included in the final sample. Two of the studies were double-blind randomized clinical trial studies. CONCLUSION: The actual effectiveness of metronidazole in controlling wound odor cannot yet be evidenced due to the absence of strong evidence from studies on the subject, despite clinical practice recommending its benefits. DOI: 10.1590/S0080-623420150000500021 PMID: 26516758 [Indexed for MEDLINE]
Appears in following Topics:
Venous Ulcers - Treatment and Prevention
Pressure Ulcers/Injuries - Treatment