Bale S, Tebbie N, Price P, et al.
British journal of nursing (Mark Allen Publishing). Date of publication 2004 Jun 10;volume 13(11):S4-11.
1. Br J Nurs. 2004 Jun 10;13(11):S4-11.
A topical metronidazole gel used to treat malodorous wounds.
Bale S(1), Tebbie N, Price P.
Author information:
(1)Nursing Research, University of Wales College of Medicine, Cardiff, Wales, UK.
Patients with malodorous wounds often experience social isolation, depression,
shame, embarrassment and poor appetite, all of which can have a negative impact
on their quality of life. The healthcare professionals caring for them face
difficult clinical challenges in terms of treating the cause and managing the
symptoms. This study employed a randomized, placebo-controlled double blind
design to investigate the effectiveness of metronidazole gel on wound malodour,
the main focus of this article. In addition, changes in self-report of mood state
were also explored. There was a 100% success rate for the metronidazole gel,
mostly within 3 days, with no adverse events reported. As there was a 76% success
rate in the placebo group, there was no significant difference in success rates
between the two groups. Odour ratings given by patients and nurses were
significantly correlated (P<0.001). There was no significant difference in mood
state between the groups over time. This study provides some evidence to support
the use of metronidazole gel in the treatment of patients with malodorous wounds,
but indicates the need for further research in this area.
DOI: 10.12968/bjon.2004.13.Sup2.13233
PMID: 15218439 [Indexed for MEDLINE]
